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Actin-Like 7A (ACTL7A) (AA 48-75), (N-Term) Antikörper

Details zu Produkt Nr. ABIN950263, Anbieter: Anmelden zum Anzeigen
Antigen
  • Tact2
  • Arp7a
  • T-actin 2
Epitop
N-Term, AA 48-75
17
15
3
2
2
1
1
1
1
Reaktivität
Human
48
7
5
Wirt
Kaninchen
45
4
Klonalität
Polyklonal
Konjugat
Unkonjugiert
5
5
5
2
2
2
Applikation
Enzyme Immunoassay (EIA), Western Blotting (WB)
42
31
6
4
Hersteller
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Immunogen KLH conjugated synthetic peptide between 48-75 amino acids from the N-terminal region of human ACTL7A
Isotyp Ig
Spezifität This antibody reacts to ACTL7A.
Kreuzreaktivität (Details) Species reactivity (tested):Human.
Reinigung Affinity chromatography on Protein A
Andere Bezeichnung ACTL7A (ACTL7A Antibody Abstract)
Hintergrund ACTL7A is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. ACTL7A (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known.Synonyms: Actin-like protein 7A, Actin-like-7-alpha
Gen-ID 10881
NCBI Accession NP_006678
Forschungsgebiet Signaling, Cytoskeleton, Microfilaments
Pathways
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Bilder des Herstellers
Western Blotting (WB) image for anti-Actin-Like 7A (ACTL7A) (AA 48-75), (N-Term) Antikörper (ABIN950263) ACTL7A Antibody (N-term) western blot analysis in NCI-H292 cell line lysates (35µg/la...
Allgemeine Veröffentlichungen Aberg, Sun, Smelser et al.: "Applying novel genome-wide linkage strategies to search for loci influencing type 2 diabetes and adult height in American Samoa." in: Human biology, Vol. 80, Issue 2, pp. 99-123, 2008 (PubMed).

Humphray, Oliver, Hunt et al.: "DNA sequence and analysis of human chromosome 9. ..." in: Nature, Vol. 429, Issue 6990, pp. 369-74, 2004 (PubMed).