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Maus anti-Human IgE Antikörper

ELISA, FACS Monoclonal BE5 IgG1 unconjugated
Produktnummer ABIN94397
  • Target Alle IgE Produkte
    IgE
    Reaktivität
    • 51
    • 31
    • 10
    • 10
    • 5
    • 4
    • 2
    • 1
    Human
    Wirt
    • 58
    • 21
    • 11
    • 10
    • 4
    • 1
    Maus
    Klonalität
    • 66
    • 32
    Monoklonal
    Applikation
    • 55
    • 40
    • 30
    • 22
    • 20
    • 15
    • 12
    • 10
    • 10
    • 8
    • 8
    • 6
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS)
    Spezifität
    The antibody BE5 reacts with human IgE, it recognizes an epitope different from the ones recognized by 4G7 and 4H10 antibodies to IgE.
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Reinheit
    > 95 % (by SDS-PAGE)
    Immunogen
    Purified human IgE.
    Klon
    BE5
    Isotyp
    IgG1
  • Applikationshinweise
    Flow cytometry: Recommended dilution: 5 μg/mL.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Target
    IgE
    Abstract
    IgE Produkte
    Hintergrund
    Immunoglobulin E (IgE) is a 180 kDa soluble protein serving as an antigen-specific unit of mast cell effector mechanisms. IgE has the lowest serum concentration of all immunoglobulins (approximately 0.5 mg/l) in healthy individuals, but upon allergen challenge its concentration in blood increases dramatically. Although biological survival of free IgE is very short (T1/2 = 2 days), it is stabilized after binding to its high affinity receptor. Unlike IgM- IgG- and IgA-committed B cells, IgE-switched B cells do not undergo clonal expansion.,Immunoglobulin E
    Molekulargewicht
    180 kDa
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