alpha Sarcomeric Actin Antikörper

Antigen: alpha Sarcomeric Actin

Klonalität: Monoklonal (5C5)

Wirt: Maus

Reaktivität: Human, Amphibien, Knochenfisch, Rind (Kuh), Meerschweinchen, Reptilien, Kaninchen, Ratte (Rattus), Schaf

Applikation: Immunhistochemie (Gefrierschnitte) (IHC (fro)), Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN93634

Produktbeschreibung

Weitere Bezeichnung: Alpha-Actin, sarcomeric

Immunogen: Purified rabbit skeletal muscle actin

Format: Ready to use

Isotyp: IgM  (Passende Sekundärantikörper)

Klon: 5C5

Beschreibung: Antibody solution in stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide**. The volume is sufficient for at least 50 immunohistochemical tests (100 ul working solution / test). Use appropriate antibody diluent.

Spezifität: Alpha-Actin sarcomeric (a-sr-1) specific for skeletal- and heart-muscle

Anwendungen

Applikationshinweise: C, P , No protease pre-treatment necessary. Blocking of endogenous peroxidase and alkaline phosphatase recommended depending on the detection system in use. neat Positive Control: Skelet muscle

Buffer: Antibody solution in stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide. The volume is sufficient for at least 50 immunohistochemical tests (100 µl working solution / test)

Lagerung: 2-8°C

Forschungsgebiet: Extrazelluläre Matrix

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Schuerch, Skalli, Seemayer et al.: "Intermediate filament proteins and actin isoforms as markers for soft tissue tumor differentiation and origin. I. Smooth muscle tumors." in: The American journal of pathology, Vol. 128, Issue 1, pp. 91-103, 1987 (PubMed).

Babai, Skalli, Schurch et al.: "Chemically induced rhabdomyosarcomas in rats. Ultrastructural, immunohistochemical, biochemical features and expression of alpha-actin isoforms." in: Virchows Archiv. B, Cell pathology including molecular pathology, Vol. 55, Issue 5, pp. 263-77, 1988 (PubMed).

Skalli, Gabbiani, Babaui et al.: "Intermediate filament proteins and actin isoforms as markers for soft tissue tumor differentiation and origin. II. Rhabdomyosarcomas." in: The American journal of pathology, Vol. 130, Issue 3, pp. 515-31, 1988 (PubMed).

Hasegawa T, Matsuno Y, Niki T et al.: "Second primary rhabdomyosarcomas in patients with bilateral retinoblastoma: a clinicopathologic and immunohistochemical study." in: Am J Surg Pathol, Vol. 22, Issue 11, pp. 1351-60, 1998 (PubMed).