Der Maus Monoklonal anti-Lipase A Antikörper (Klon 9G7F12-7G6D7) (ABIN3210008) detektiert spezifisch Lipase A in WB und ELISA.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
ELISA: 1:10,000, WB: 1:500-1:2000, Optimal conditions should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
Lot specific
Buffer
Purified antibody supplied in PBS containing 0.03 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handhabung
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 4 °C for short term storage. Store at -20 °C for long term storage.
Target
Lipase A (LIPA)
(Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))
Andere Bezeichnung
LAL
Hintergrund
LAL functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides which are taken up by receptor-mediated endocytosis. An inherited deficiency or low activity of human lysosomal acid lipase results in the intralysosomal storage of the respective lipid substrates. So it is also responsible for the rare conditions of Wolman disease and cholesteryl ester storage disease (CESD). As the enzyme is synthesized by all nucleated cells, lipid-laden cells are found in all organs, particularly in liver, spleen, the adrenal and the hemopoietic system, and in the intestine as well as in the lymph nodes, lungs, testes, and ovaries. Synonyms: Monoclonal LAL antibody, Anti-LAL antibody, Lysosomal acid lipase antibody.