CIITA Antikörper (C-Term)

Produktnummer ABIN927649

Produktdetails anti-CIITA Antikörper

Target: CIITA (Class II, Major Histocompatibility Complex, Transactivator (CIITA))

Bindungsspezifität: C-Term

Reaktivität: Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CIITA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Ratte (Rattus), Hund

Aufreinigung: Purified

Immunogen: C2 TA antibody was raised in rabbit using the C terminal of C2 A as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.125 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

C2TA Blocking Peptide, catalog no. 33R-5700, is also available for use as a blocking control in assays to test for specificity of this C2TA antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu CIITA

Target: CIITA (Class II, Major Histocompatibility Complex, Transactivator (CIITA))

Andere Bezeichnung: C2TA (CIITA Produkte)

Synonyme: CIITA antikoerper, C2ta antikoerper, EG669998 antikoerper, Gm9475 antikoerper, C2TA antikoerper, CIITAIV antikoerper, MHC2TA antikoerper, NLRA antikoerper, Mhc2ta antikoerper, class II, major histocompatibility complex, transactivator antikoerper, class II major histocompatibility complex transactivator antikoerper, MHC class II transactivator antikoerper, class II transactivator antikoerper, CIITA antikoerper, LOC710761 antikoerper, ciita antikoerper, LOC100443575 antikoerper, Ciita antikoerper, LOC100736732 antikoerper

Hintergrund: C2ta is essential for transcriptional activity of the HLA class II promoter, activation is via the proximal promoter. No DNA binding of in vitro translated CIITA was detected. C2ta may act in a coactivator-like fashion through protein-protein interactions by contacting factors binding to the proximal MHC class II promoter, to elements of the transcription machinery, or both. Alternatively it may activate HLA class II transcription by modifying proteins that bind to the MHC class II promoter. Synonyms: Polyclonal C2TA antibody, Anti-C2TA antibody.

Pathways: Cancer Immune Checkpoints