PSMC3IP Antikörper (Middle Region)

Produktnummer ABIN925964

Produktdetails anti-PSMC3IP Antikörper

Target: PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))

Bindungsspezifität: Middle Region

Reaktivität: Maus, Human, Ratte, Hund, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMC3IP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Ratte (Rattus), Maus, Hund, Rind (Kuh)

Immunogen: PSMC3 IP antibody was raised in rabbit using the middle region of PSMC3 P as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 1.25 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

PSMC3IP Blocking Peptide, catalog no. 33R-8034, is also available for use as a blocking control in assays to test for specificity of this PSMC3IP antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu PSMC3IP

Target: PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))

Andere Bezeichnung: PSMC3IP (PSMC3IP Produkte)

Synonyme: PSMC3IP antikoerper, Arabidopsis Hop2 homolog antikoerper, T6J4.9 antikoerper, T6J4_9 antikoerper, C79099 antikoerper, GT198 antikoerper, HOP2 antikoerper, Tbpip antikoerper, HUMGT198A antikoerper, ODG3 antikoerper, TBPIP antikoerper, Gt198 antikoerper, zgc:86785 antikoerper, PSMC3 interacting protein antikoerper, homologous-pairing protein 2 homolog antikoerper, Homologous-pairing protein 2 homolog antikoerper, homologous-pairing protein 2 homolog-like antikoerper, Tat-binding protein 1(Tbp-1)-interacting protein (TBPIP) antikoerper, proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein antikoerper, PSMC3 interacting protein L homeolog antikoerper, PSMC3IP antikoerper, LOC726449 antikoerper, LOC100165513 antikoerper, hop2 antikoerper, psmc3ip antikoerper, LOC100633854 antikoerper, LOC100650062 antikoerper, LOC789362 antikoerper, AHP2 antikoerper, Psmc3ip antikoerper, psmc3ip.L antikoerper

Hintergrund: PSMC3IP plays an important role in meiotic recombination. It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. It may inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3. Synonyms: Polyclonal PSMC3IP antibody, Anti-PSMC3IP antibody, PSMC3 interacting protein antibody, GT198 antibody, HOP2 antibody, TBPIP antibody.