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WNK4 Antikörper (Alexa Fluor 555)

WNK4 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal Alexa Fluor 555
Produktnummer ABIN920033
  • Target Alle WNK4 Antikörper anzeigen
    WNK4 (WNK Lysine Deficient Protein Kinase 4 (WNK4))
    Reaktivität
    • 45
    • 29
    • 25
    • 4
    • 1
    Human, Maus, Ratte
    Wirt
    • 46
    • 2
    Kaninchen
    Klonalität
    • 46
    • 2
    Polyklonal
    Konjugat
    • 13
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser WNK4 Antikörper ist konjugiert mit Alexa Fluor 555
    Applikation
    • 28
    • 25
    • 8
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human WNK4
    Isotyp
    IgG
    Top Product
    Discover our top product WNK4 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    WNK4 (WNK Lysine Deficient Protein Kinase 4 (WNK4))
    Andere Bezeichnung
    WNK4 (WNK4 Produkte)
    Synonyme
    WNK4 antikoerper, PHA2B antikoerper, PRKWNK4 antikoerper, 2010002J11Rik antikoerper, Pha2b antikoerper, Prkwnk4 antikoerper, Ac2-059 antikoerper, WNK lysine deficient protein kinase 4 antikoerper, WNK4 antikoerper, Wnk4 antikoerper
    Hintergrund

    Synonyms: PHA 2B, PHA2B, PRKWNK 4, PRKWNK4, Protein kinase lysine deficient 4, Protein kinase with no lysine 4, Serine/threonine protein kinase WNK4, WNK lysine deficient protein kinase 4, WNK4_HUMAN.

    Background: Regulates the activity of the thiazide-sensitive Na-Cl cotransporter, SLC12A3, by phosphorylation which appears to prevent membrane trafficking of SLC12A3. Also inhibits the renal K(+)channel, KCNJ1, via a kinase-independent mechanism by which it induces clearance of the protein from the cell surface by clathrin-dependent endocytosis. WNK4 appears to act as a molecular switch that can vary the balance between NaCl reabsorption and K(+)secretion to maintain integrated homeostasis.

    Gen-ID
    65266
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