Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

TUSC2 Antikörper (AA 31-100) (Alexa Fluor 488)

TUSC2 Reaktivität: Human WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 488
Produktnummer ABIN919018
  • Target Alle TUSC2 Antikörper anzeigen
    TUSC2 (Tumor Suppressor Candidate 2 (TUSC2))
    Bindungsspezifität
    • 14
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 31-100
    Reaktivität
    • 29
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 27
    • 2
    • 1
    Kaninchen
    Klonalität
    • 29
    • 1
    Polyklonal
    Konjugat
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TUSC2 Antikörper ist konjugiert mit Alexa Fluor 488
    Applikation
    • 27
    • 15
    • 12
    • 12
    • 9
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human TUSC2
    Isotyp
    IgG
    Top Product
    Discover our top product TUSC2 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    TUSC2 (Tumor Suppressor Candidate 2 (TUSC2))
    Andere Bezeichnung
    TUSC2 (TUSC2 Produkte)
    Synonyme
    C3orf11 antikoerper, FUS1 antikoerper, PAP antikoerper, PDAP2 antikoerper, TUSC2 antikoerper, 1190001E22Rik antikoerper, AA407686 antikoerper, Fus1 antikoerper, Lgcc antikoerper, Pdap2 antikoerper, zgc:92701 antikoerper, zgc:153746 antikoerper, tumor suppressor candidate 2 antikoerper, tumor suppressor candidate 2 L homeolog antikoerper, tumor suppressor candidate 2b antikoerper, tumor suppressor candidate 2a antikoerper, TUSC2 antikoerper, tusc2.L antikoerper, Tusc2 antikoerper, tusc2b antikoerper, tusc2a antikoerper
    Hintergrund

    Synonyms: C3orf11, FUS1, Fusion 1 protein, PAP, PDAP2, PDGFA associated protein 2, Tumor suppressor candidate 2, TUSC 2, TUSC2_HUMAN.

    Background: TUSC2/FUS1 is a novel tumor suppressor gene identified in the human chromosome 3p21.3 region where allele losses and genetic alterations occur early and frequently for many human cancers. Expression of TUSC2 protein is absent or reduced in the majority of lung cancers and premalignant lung lesions. Restoration of TUSC2 function in 3p21.3-deficient non-small cell lung carcinoma cells significantly inhibits tumor cell growth by induction of apoptosis and alteration of cell cycle kinetics. TUSC2 may induce apoptosis through the activation of the intrinsic mitochondrial-dependent and Apaf-1-associated pathways and inhibit the function of protein tyrosine kinases including EGFR, PDGFR, AKT, c-Abl, and c-Kit.

    Gen-ID
    11334
Sie sind hier:
Kundenservice