THAP1 Antikörper (AA 121-213) (Alexa Fluor 488)

Produktnummer ABIN917553

Produktdetails anti-THAP1 Antikörper (Alexa Fluor 488)

Target: THAP1 (THAP Domain Containing, Apoptosis Associated Protein 1 (THAP1))

Bindungsspezifität: AA 121-213

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser THAP1 Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human THAP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu THAP1

Target: THAP1 (THAP Domain Containing, Apoptosis Associated Protein 1 (THAP1))

Andere Bezeichnung: THAP1 (THAP1 Produkte)

Synonyme: THAP1 antikoerper, thap1-a antikoerper, DYT6 antikoerper, 4833431A01Rik antikoerper, AW490810 antikoerper, zgc:136597 antikoerper, THAP domain containing, apoptosis associated protein 1 antikoerper, THAP domain containing 1 antikoerper, THAP domain containing, apoptosis associated protein 1 L homeolog antikoerper, thap1 antikoerper, THAP1 antikoerper, thap1.L antikoerper, Thap1 antikoerper

Hintergrund:

Synonyms: Nuclear proapoptotic factor, THAP 1, THAP domain containing apoptosis associated protein 1, THAP domain containing protein 1, THAP domain protein 1, THAP1_HUMAN.

Background: THAP1 contains a THAP domain, a zinc-dependent DNA-binding domain. It colocalizes with the apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies and is a pro-apoptopic protein that potentiates both serum-withdrawal and TNF-induced apoptosis. It is a physiologic regulator of endothelial cell proliferation and cell-cycle progression, two essential processes for angiogenesis.

Gen-ID: 55145