Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

CDC14B Antikörper (AA 65-160) (Cy5.5)

CDC14B Reaktivität: Human, Maus, Ratte IF (cc), IF (p) Wirt: Kaninchen Polyclonal Cy5.5
Produktnummer ABIN889448
  • Target Alle CDC14B Antikörper anzeigen
    CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))
    Bindungsspezifität
    • 14
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 65-160
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 20
    • 4
    Kaninchen
    Klonalität
    • 24
    Polyklonal
    Konjugat
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CDC14B Antikörper ist konjugiert mit Cy5.5
    Applikation
    • 12
    • 12
    • 10
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CDC14B
    Isotyp
    IgG
    Top Product
    Discover our top product CDC14B Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))
    Andere Bezeichnung
    CDC14B (CDC14B Produkte)
    Synonyme
    CDC14B antikoerper, 2810432N10Rik antikoerper, A530086E13Rik antikoerper, AA472821 antikoerper, CDC14B3 antikoerper, Cdc14B1 antikoerper, Cdc14B2 antikoerper, hCDC14B antikoerper, Dual specificity protein phosphatase CDC14B antikoerper, dual specificity protein phosphatase CDC14B antikoerper, cell division cycle 14B antikoerper, CDC14 cell division cycle 14B antikoerper, Bm1_19115 antikoerper, LOAG_10083 antikoerper, CDC14B antikoerper, cdc14b antikoerper, Cdc14b antikoerper
    Hintergrund

    Synonyms: CDC14B3, Cdc14B1, Cdc14B2, hCDC14B, Dual specificity protein phosphatase CDC14B, CDC14 cell division cycle 14 homolog B, CDC14B

    Background: Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint: following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome (APC/C). Dephosphorylates SIRT2 around early anaphase. Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to the ubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified by proline-directed kinases.

    Gen-ID
    8555
    UniProt
    O60729
Sie sind hier:
Kundenservice