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ADAMTSL2 Antikörper (AA 522-580) (Alexa Fluor 350)

ADAMTSL2 Reaktivität: Human WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 350
Produktnummer ABIN881387
  • Target Alle ADAMTSL2 Antikörper anzeigen
    ADAMTSL2 (ADAMTS-Like 2 (ADAMTSL2))
    Bindungsspezifität
    • 14
    • 1
    • 1
    • 1
    • 1
    AA 522-580
    Reaktivität
    • 21
    • 3
    • 1
    • 1
    • 1
    Human
    Wirt
    • 20
    • 1
    Kaninchen
    Klonalität
    • 21
    Polyklonal
    Konjugat
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ADAMTSL2 Antikörper ist konjugiert mit Alexa Fluor 350
    Applikation
    • 19
    • 12
    • 12
    • 7
    • 5
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human
    Homologie
    Mouse,Rat
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ADAMTSL2
    Isotyp
    IgG
    Top Product
    Discover our top product ADAMTSL2 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    ADAMTSL2 (ADAMTS-Like 2 (ADAMTSL2))
    Andere Bezeichnung
    ADAMTSL2 (ADAMTSL2 Produkte)
    Synonyme
    ADAMTSL2 antikoerper, GPHYSD1 antikoerper, A930008K15Rik antikoerper, tcp-1 antikoerper, RGD1305459 antikoerper, ADAMTS-like 2 antikoerper, ADAMTS like 2 antikoerper, ADAMTS-like protein 2 antikoerper, ADAMTSL2 antikoerper, adamtsl2 antikoerper, LOC100589493 antikoerper, Adamtsl2 antikoerper
    Hintergrund

    Synonyms: ADAMTS like 2, ADAMTS like protein 2, ADAMTS-like protein 2, ADAMTSL 2, ADAMTSL-2, ADAMTSL2, ATL2_HUMAN.

    Background: ADAMTS (A Disintegrin And Metalloproteinase Domain with Thrombospondin type 1 Modules) is a family of zinc-dependent proteases that are implicated in a variety of normal and pathological conditions, including arthritis and cancer. ADAMTS protein family members contain an amino-terminal propeptide domain, a metalloproteinase domain, a disintegrin-like domain and a carboxy-terminus that contains a varying number of Thrombospondin type 1 (TSP-1) motifs. ADAMTS-L2 (ADAMTS-like protein 2) is a 951 amino acid secreted protein that is highly expressed in lung, kidney and liver. Mutations in the gene encoding ADAMTS are the cause of geleophysic dysplasia, an autosomal recessive disorder characterized by cardiac vavular anomalies, short stature, thick skin and brachydactyly. In individuals affected with geleophysic dysplasia, there is a significant increase in total active TGF-beta 1 and nuclear locations of p-SAMD2 in fibroblasts. Interestingly, ADAMTS-L2 interacts with LTBP-1, a glycoprotein that is part of the platelet-derived TGF-beta 1 complex.

    Gen-ID
    9719
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