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CHMP4B Antikörper (AA 101-200)

CHMP4B Reaktivität: Human, Ratte ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN872575
  • Target Alle CHMP4B Antikörper anzeigen
    CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))
    Bindungsspezifität
    • 14
    • 8
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    AA 101-200
    Reaktivität
    • 44
    • 21
    • 14
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Ratte
    Wirt
    • 43
    • 1
    Kaninchen
    Klonalität
    • 43
    • 1
    Polyklonal
    Konjugat
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CHMP4B Antikörper ist unkonjugiert
    Applikation
    • 20
    • 18
    • 18
    • 12
    • 12
    • 12
    • 4
    • 3
    • 2
    • 2
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human, Ratte
    Homologie
    Mouse,Dog,Cow,Pig,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CHMP4B/CHMP4C
    Isotyp
    IgG
  • Applikationshinweise
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))
    Andere Bezeichnung
    Chmp4b+Chmp4c (CHMP4B Produkte)
    Synonyme
    C20orf178 antikoerper, CHMP4A antikoerper, CTPP3 antikoerper, CTRCT31 antikoerper, SNF7 antikoerper, SNF7-2 antikoerper, Shax1 antikoerper, VPS32B antikoerper, Vps32-2 antikoerper, dJ553F4.4 antikoerper, 2010012F05Rik antikoerper, C76846 antikoerper, Snf7-2 antikoerper, RGD1309846 antikoerper, RGD1565889 antikoerper, CHMP4b antikoerper, chmp4b antikoerper, chmp4b.S antikoerper, CHMP4c antikoerper, c20orf178 antikoerper, wu:fc96b02 antikoerper, zgc:55566 antikoerper, charged multivesicular body protein 4B antikoerper, charged multivesicular body protein 4Ba antikoerper, charged multivesicular body protein 4B L homeolog antikoerper, charged multivesicular body protein 4Bb antikoerper, CHMP4B antikoerper, Chmp4b antikoerper, chmp4ba antikoerper, chmp4b.L antikoerper, chmp4bb antikoerper
    Hintergrund

    Synonyms: CHMP4B: Charged multivesicular body protein 4b, Chromatin-modifying protein 4b, CHMP4b, SNF7 homolog associated with Alix 1, SNF7-2, hSnf7-2, Vacuolar protein sorting-associated protein 32-2, Vps32-2, hVps32-2 CHMP4C: Charged multivesicular body protein 4C, Chromatin-modifying protein 4C, CHMP4C, SNF7 homolog associated with Alix 3 SNF7-3, hSnf7-3, Vacuolar protein sorting-associated protein 32-3, Vps32-3, hVps32-3

    Background: Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses).

    Gen-ID
    128866, 92421
    UniProt
    Q9H444, Q96CF2
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