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Doublecortin Antikörper (AA 413-417)

DCX Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN871559
  • Target Alle Doublecortin (DCX) Antikörper anzeigen
    Doublecortin (DCX)
    Bindungsspezifität
    • 7
    • 7
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 413-417
    Reaktivität
    • 111
    • 73
    • 67
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 102
    • 12
    • 2
    • 2
    Kaninchen
    Klonalität
    • 97
    • 21
    Polyklonal
    Konjugat
    • 65
    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Doublecortin Antikörper ist unkonjugiert
    Applikation
    • 75
    • 41
    • 33
    • 13
    • 12
    • 11
    • 9
    • 8
    • 8
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Spezifität
    The antibody detects endogenous level of total Doublecortin protein.
    Aufreinigung
    Affinity purified
    Immunogen
    Peptide sequence around AA 413-417 ( P-T-S-P-G) derived from Human Doublecortin. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
    Top Product
    Discover our top product DCX Primärantikörper
  • Applikationshinweise
    Western blotting: 1:500-1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Target
    Doublecortin (DCX)
    Andere Bezeichnung
    Doublecortin (DCX Produkte)
    Synonyme
    DCX antikoerper, DBCN antikoerper, DC antikoerper, LISX antikoerper, SCLH antikoerper, XLIS antikoerper, Dbct antikoerper, 18C15.5 antikoerper, doublecortin antikoerper, DCX antikoerper, Dcx antikoerper
    Hintergrund
    Seems to be required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCAMKL1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with LIS-1 of an overlapping, but distinct, signaling pathways that promote neuronal migration.
    Molekulargewicht
    40-45 kDa
    Gen-ID
    1641
    NCBI Accession
    NP_000546
    UniProt
    O43602
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