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Caspase 3 Antikörper (AA 29-33)

Name: Caspase 3 Antikörper (AA 29-33)
SKU: ABIN871475
Price: 268.4 EUR
Availability: InStock

CASP3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated

(1 reference)

Produktnummer ABIN871475

Datenblatt (PDF)

Target Alle Caspase 3 (CASP3) Antikörper anzeigen

Caspase 3 (CASP3)
Bindungsspezifität
19

16

16

16

16

16

16

15

14

13

12

11

10

9

8

7

7

6

6

6

5

5

4

4

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 29-33
Reaktivität
281

196

149

31

17

10

10

9

7

7

5

5

4

3

3

2

1

1

1
Human
Wirt
281

42

4

2

2
Kaninchen
Passende Sekundärantikörper
Klonalität
274

56
Polyklonal
Konjugat
161

27

21

14

11

11

9

9

9

9

9

6

6

6

6

6

6

2

2

1
Dieser Caspase 3 Antikörper ist unkonjugiert
Applikation
254

109

104

85

79

65

52

36

34

29

28

20

10

6

3

2

2

1

1

1

1

1

1
Western Blotting (WB)

Spezifität

The antibody detects endogenous level of total Caspase 3 protein.

Aufreinigung

Affinity purified

Immunogen

Peptide sequence around AA 29-33 (S-G-I-S-L) derived from Caspase 3. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

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anti-Caspase 3 (CASP3) (pSer150) antibody
CASP3 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Caspase 3 (CASP3) (AA 100-200) antibody
CASP3 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Western blotting: 1:1000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Shen, Song, An, Li, Wu, Ruan, Hu, Hu: "The use of hollow mesoporous silica nanospheres to encapsulate bortezomib and improve efficacy for non-small cell lung cancer therapy." in: Biomaterials, Vol. 35, Issue 1, pp. 316-26, (2013) (PubMed).
Target

Caspase 3 (CASP3)

Andere Bezeichnung

Caspase 3 (CASP3 Produkte)

Synonyme

CPP32 antikoerper, CPP32B antikoerper, SCA-1 antikoerper, A830040C14Rik antikoerper, AC-3 antikoerper, Apopain antikoerper, CC3 antikoerper, Caspase-3 antikoerper, Lice antikoerper, Yama antikoerper, mldy antikoerper, xcpp32 antikoerper, casp3 antikoerper, zgc:100890 antikoerper, CASP-3 antikoerper, caspase-3 antikoerper, caspase 3 antikoerper, caspase 3 S homeolog antikoerper, caspase 3, apoptosis-related cysteine peptidase a antikoerper, caspase 3, apoptosis-related cysteine peptidase antikoerper, CASP3 antikoerper, Casp3 antikoerper, casp3.S antikoerper, casp3a antikoerper

Hintergrund

Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.

Molekulargewicht

17 kDa

Gen-ID

836

NCBI Accession

NP_004337

UniProt

P42574

Pathways

Apoptose, Caspase Kaskade in der Apoptose, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation