TRPV3 Antikörper (AA 458-474)

Produktnummer ABIN863127

Produktdetails anti-TRPV3 Antikörper

Target: TRPV3 (Transient Receptor Potential Cation Channel, Subfamily V, Member 3 (TRPV3))

Bindungsspezifität: AA 458-474

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TRPV3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF), Antibody Array (AA)

Spezifität: Detects ~70 kDa.

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Protein G Purified

Immunogen: Synthetic peptide amino acids 458-474 (cytoplasmic C-terminus) of rat TrpV3

Klon: N15-39 (Formerly S15-39)

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

• WB (1:1000)
• IHC (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Kommentare:

1 μg/ml of ABIN863127 was sufficient for detection of TrpV3 in 10 μg of COS-1 cell lysate transiently transfected with TrpV3 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Referenzen für anti-TRPV3 Antikörper (ABIN863127)

Liebe, Liebe, Sponder, Mergler, Stumpff: "Effects of butyrate- on ruminal Ca2+ transport: evidence for the involvement of apically expressed TRPV3 and TRPV4 channels." in: Pflugers Archiv : European journal of physiology, Vol. 474, Issue 3, pp. 315-342, (2022) (PubMed).

Manneck, Manz, Braun, Rosendahl, Stumpff: "The TRPA1 Agonist Cinnamaldehyde Induces the Secretion of HCO3- by the Porcine Colon." in: International journal of molecular sciences, Vol. 22, Issue 10, (2021) (PubMed).

Liebe, Liebe, Sponder, Hedtrich, Stumpff: "Beyond Ca2+ signalling: the role of TRPV3 in the transport of NH4." in: Pflügers Archiv : European journal of physiology, (2021) (PubMed).

Liebe, Liebe, Kaessmeyer, Sponder, Stumpff: "The TRPV3 channel of the bovine rumen: localization and functional characterization of a protein relevant for ruminal ammonia transport." in: Pflügers Archiv : European journal of physiology, (2020) (PubMed).

Details zu TRPV3

Target: TRPV3 (Transient Receptor Potential Cation Channel, Subfamily V, Member 3 (TRPV3))

Andere Bezeichnung: TRPV3 (TRPV3 Produkte)

Synonyme: OLMS antikoerper, VRL3 antikoerper, 1110036I10Rik antikoerper, AI644701 antikoerper, Nh antikoerper, transient receptor potential cation channel subfamily V member 3 antikoerper, transient receptor potential cation channel, subfamily V, member 3 antikoerper, TRPV3 antikoerper, Trpv3 antikoerper

Hintergrund: The TRPV3 protein belongs to a family of non-selective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermo sensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. The gene lies in close proximity to another family member (TRPV1) gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels (1, 2).

Gen-ID: 497948

NCBI Accession: NP_001020928

UniProt: Q4QYD9