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IL12A Antikörper
IL12A
Reaktivität: Human, Hund, Schwein
IHC (p), EIA
Wirt: Ziege
Polyclonal
unconjugated
Produktdetails anti-IL12A Antikörper
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Target
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IL12A
(Interleukin 12 alpha (IL12A))
Reaktivität
Alle Reaktivitäten für IL12A Antikörper
Human, Hund, Schwein
Wirt
Alle Wirte für IL12A Antikörper
Ziege
Klonalität
Alle Klonalitäten für IL12A Antikörper
Polyklonal
Konjugat
Alle Konjugate für IL12A Antikörper
Dieser IL12A Antikörper ist unkonjugiert
Applikation
Alle Applikationen für IL12A Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Spezifität
Recognizes Interleukin-12 alpha / IL12A.
Kreuzreaktivität (Details)
Species reactivity (expected):Canine (Dog), Pig. Species reactivity (tested):Human.
Aufreinigung
Immunoaffinity Chromatography
Immunogen
Synthetic peptide - KLH conjugated of Human IL12A
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Discover our top product IL12A Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
0.5 mg/mL
Buffer
Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid freeze-thaw cycles.
Details zu IL12A
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Target
IL12A
(Interleukin 12 alpha (IL12A))
Andere Bezeichnung
Interleukin-12 alpha / IL12A (IL12A Produkte )
Synonyme
CLMF antikoerper, IL-12A antikoerper, NFSK antikoerper, NKSF1 antikoerper, P35 antikoerper, CLMF2 antikoerper, IL-12B antikoerper, NKSF antikoerper, NKSF2 antikoerper, p40 antikoerper, Il-12b antikoerper, Il12p40 antikoerper, Il-12p40 antikoerper, Il12 antikoerper, IL-12p40 antikoerper, IL-12p35 antikoerper, Il-12a antikoerper, Ll12a antikoerper, p35 antikoerper, IL12p35 antikoerper, Il-12 p35 antikoerper, IL12p40 antikoerper, IL12 antikoerper, IL-12 p35 antikoerper, interleukin 12A antikoerper, interleukin 12B antikoerper, interleukin 12b antikoerper, interleukin 12a antikoerper, Interleukin 12 level antikoerper, IL12A antikoerper, IL12B antikoerper, Il12b antikoerper, Il12a antikoerper, IL12 antikoerper, il12a antikoerper
Hintergrund
Interleukin 12 (IL12) can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine activated killer cells, and stimulate the production of IFN gamma by resting PBMC. IL12 induces IFN gamma, TNF alpha production in T and NK cells, costimulation of PBL proliferation, proliferation/differentiation of TH1 T lymphocytes. It is downregulated by IL10, homodimeric p40 antagonistic to functional p70 heterodimer. IL12R beta 1 binds p40 but when dimeric with IL12R beta 2 binds p35.Synonyms: CLMF p35, Cytotoxic lymphocyte maturation factor 35 kDa subunit, IL-12 subunit p35, IL-12A, NK cell stimulatory factor chain 1, NKSF1
Gen-ID
3592
NCBI Accession
NP_000873
Pathways
JAK-STAT Signalweg , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Activated T Cell Proliferation
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