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NLRP5 Antikörper (C-Term)

NLRP5 Reaktivität: Human, Maus, Ratte WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN783707
  • Target Alle NLRP5 Antikörper anzeigen
    NLRP5 (NLR Family, Pyrin Domain Containing 5 (NLRP5))
    Bindungsspezifität
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 12
    • 8
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 11
    • 1
    Kaninchen
    Klonalität
    • 12
    Polyklonal
    Konjugat
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NLRP5 Antikörper ist unkonjugiert
    Applikation
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects NLRP5 at C-term.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, mouse, rat
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    14 amino acid peptide near the carboxy terminus of human NALP5
    Top Product
    Discover our top product NLRP5 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Target
    NLRP5 (NLR Family, Pyrin Domain Containing 5 (NLRP5))
    Andere Bezeichnung
    NLRP5 (NLRP5 Produkte)
    Synonyme
    CLR19.8 antikoerper, MATER antikoerper, NALP5 antikoerper, PAN11 antikoerper, PYPAF8 antikoerper, Mater antikoerper, Nalp5 antikoerper, Op1 antikoerper, NLR family pyrin domain containing 5 antikoerper, NLR family, pyrin domain containing 5 antikoerper, NLRP5 antikoerper, Nlrp5 antikoerper
    Hintergrund
    NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP5, also known as MATER, is a maternal gene required for early embryonic development in mice. Increased NALP5 expression was observed in two neuronal injury models, and transient expression of recombinant NALP5 in neurons induced caspase-3 activation and apoptosis, suggesting that NALP5 also plays a role in caspase activation and apoptosis in injured neurons, and may thus represent a novel target for therapeutic treatment in neurodegenerative disorders.Synonyms: LRR and PYD domains-containing protein 5, MATER, NALP5
    Gen-ID
    126206
    NCBI Accession
    NP_703148
    UniProt
    P59047
    Pathways
    Inflammasome
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