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MFSD2A Antikörper (AA 331-430) (Cy3)

MFSD2A Reaktivität: Human, Maus, Ratte WB, FACS, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Cy3
Produktnummer ABIN762029
  • Target Alle MFSD2A Antikörper anzeigen
    MFSD2A (Major Facilitator Superfamily Domain Containing 2A (MFSD2A))
    Bindungsspezifität
    • 15
    • 2
    • 2
    AA 331-430
    Reaktivität
    • 19
    • 18
    • 18
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 19
    Kaninchen
    Klonalität
    • 19
    Polyklonal
    Konjugat
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MFSD2A Antikörper ist konjugiert mit Cy3
    Applikation
    • 19
    • 13
    • 12
    • 12
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Dog,Cow,Pig,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MFSD2A
    Isotyp
    IgG
    Top Product
    Discover our top product MFSD2A Primärantikörper
  • Applikationshinweise
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    MFSD2A (Major Facilitator Superfamily Domain Containing 2A (MFSD2A))
    Andere Bezeichnung
    MFSD2A (MFSD2A Produkte)
    Synonyme
    1700018O18Rik antikoerper, Mfsd2 antikoerper, RGD1310174 antikoerper, MFSD2 antikoerper, NLS1-A antikoerper, Sodium-dependent LPC symporter 1-A antikoerper, mfsd2a antikoerper, zgc:101615 antikoerper, mfsd2 antikoerper, NLS1-B antikoerper, Sodium-dependent LPC symporter 1-B antikoerper, mfsd2b antikoerper, zgc:101069 antikoerper, major facilitator superfamily domain containing 2A antikoerper, major facilitator superfamily domain containing 2aa antikoerper, major facilitator superfamily domain containing 2A L homeolog antikoerper, major facilitator superfamily domain containing 2ab antikoerper, MFSD2A antikoerper, mfsd2a antikoerper, Mfsd2a antikoerper, mfsd2aa antikoerper, mfsd2a.L antikoerper, mfsd2ab antikoerper
    Hintergrund

    Synonyms: NLS1, MFSD2, Sodium-dependent lysophosphatidylcholine symporter 1, Sodium-dependent LPC symporter 1, Major facilitator superfamily domain-containing protein 2A, MFSD2A, HMFN0656, PP9177, UNQ300/PRO341

    Background: Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function. Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain. Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fatty acids such LPC oleate and LPC palmitate with a minimum acyl chain length of 14 carbons. Does not transport docosahexaenoic acid in unesterified fatty acid. Specifically required for blood-brain barrier formation and function, probably by mediating lipid transport. Not required for central nervous system vascular morphogenesis (By similarity). Acts as a transporter for tunicamycin, an inhibitor of asparagine-linked glycosylation. In placenta, acts as a receptor for ERVFRD-1/syncytin-2 and is required for trophoblast fusion (PubMed:18988732).

    Gen-ID
    84879
    UniProt
    Q8NA29
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