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PCDHGB5 Antikörper (AA 21-120) (Cy7)

PCDHGB5 Reaktivität: Human WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Cy7
Produktnummer ABIN758477
  • Target Alle PCDHGB5 Antikörper anzeigen
    PCDHGB5 (Protocadherin gamma Subfamily B, 5 (PCDHGB5))
    Bindungsspezifität
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 21-120
    Reaktivität
    • 26
    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 25
    • 1
    Kaninchen
    Klonalität
    • 26
    Polyklonal
    Konjugat
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PCDHGB5 Antikörper ist konjugiert mit Cy7
    Applikation
    • 20
    • 12
    • 12
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PCDHGB5
    Isotyp
    IgG
    Top Product
    Discover our top product PCDHGB5 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    PCDHGB5 (Protocadherin gamma Subfamily B, 5 (PCDHGB5))
    Andere Bezeichnung
    PCDHGB5 (PCDHGB5 Produkte)
    Synonyme
    PCDH-GAMMA-B5 antikoerper, protocadherin gamma subfamily B, 5 antikoerper, PCDHGB5 antikoerper, Pcdhgb5 antikoerper
    Hintergrund

    Synonyms: PCDH gamma B5, PCDHGB 5, Protocadherin gamma B5, Protocadherin gamma subfamily B 5, PCDGH_HUMAN.

    Background: PCDHGB5 is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

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