Adenylate Cyclase 3 (ADCY3) Antikörper (PE)

Antigen: Adenylate Cyclase 3 (ADCY3)

Synonyme: AC3, KIAA0511, AC8, ADCY3, HBAC1, mKIAA0511, ADCY8, si:ch211-153j24.5, Adcy3, MGC53136, MGC145869, Amac3, GB11637

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus), Schwein, Hund, Pferd, Rind (Kuh), Kaninchen

Konjugat: PE

Applikation: Durchflusszytometrie (FACS), Immunfluoreszenz (IF)

Produktnummer: ABIN752663

Produktbeschreibung

Weitere Bezeichnung: ADCY3

Immunogen: Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human ADCY3。

Format: Lyophilized

Wiederherstellung: Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)

Beschreibung: Synonym: AC3, adenylate cyclase 3, Adenylate cyclase type III.

Spezifität: Excitation / Emission Wavelengths: 565nm/578nm

Kommentare:

The cAMP synthesizing enzymes are found in two forms: cytosolic (soluble) and membrane-bound (particulate). Stimulation of adenylate cyclases produce cAMP form ATP in response to the activation of GPCRs by various hormones

neurotransmitters and other regulatory molecules. cAMP

in subsequent steps down the signal transduction pathway

can stimulate cAMP-dependent protein kinase A (cPKA)

and several other target molecules. Activation of cPKA can phosphorylate a broad range of substrates that regulate various metabolic pathways

gene expression

and affect memory functions etc. The stimulation of adenylate cyclases starts with interactions with GPCRs mediated signals initiated by Gs and Gi heterotrimeric G-proteins.

Anwendungen

Applikationshinweise: Flow-Cyt(1:50-200), IF(1:50-200)

Reinigung: Antibodies are purified by protein A and peptide affinity chromatography.

Buffer: 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

Lagerung: Ship at room temperature. Store at -20°C

Forschungsgebiet: Krebs

Beschränkungen: Nur für Forschungszwecke einsetzbar