CACNA1D Antikörper (AA 1201-1300)

Produktnummer ABIN751333

Produktdetails anti-CACNA1D Antikörper

Target: CACNA1D (Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D))

Bindungsspezifität: AA 1201-1300

Reaktivität: Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CACNA1D Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Affe, Ratte

Homologie: Human,Mouse,Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CaV1.3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CACNA1D Antikörper (ABIN751333)

Lobeck, Donnelly, Dupree, Mahe, McNeal, Mohanty, Tiao: "Rhesus rotavirus VP6 regulates ERK-dependent calcium influx in cholangiocytes." in: Virology, Vol. 499, pp. 185-195, (2016) (PubMed).

Details zu CACNA1D

Target: CACNA1D (Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D))

Andere Bezeichnung: CACH3/CaV1.3 (CACNA1D Produkte)

Synonyme: cacna1d antikoerper, cav1.3a antikoerper, isl antikoerper, si:dz136d19.3 antikoerper, si:dz223c6.1 antikoerper, ca(v)1.3 antikoerper, cav1.3 antikoerper, CACH3 antikoerper, CACN4 antikoerper, CACNL1A2 antikoerper, CCHL1A2 antikoerper, Cav1.3 antikoerper, SANDD antikoerper, 8430418G19Rik antikoerper, C79217 antikoerper, Cacnl1a2 antikoerper, Cchl1a antikoerper, Cchl1a2 antikoerper, D-LTCC antikoerper, calcium channel, voltage-dependent, L type, alpha 1D subunit, a antikoerper, calcium voltage-gated channel subunit alpha1 D antikoerper, calcium channel, voltage-dependent, L type, alpha 1D subunit antikoerper, calcium channel, voltage-dependent, L type, alpha 1D subunit L homeolog antikoerper, cacna1da antikoerper, CACNA1D antikoerper, cacna1d antikoerper, cacna1d.L antikoerper, Cacna1d antikoerper

Hintergrund:

Synonyms: CACH3, CACN4, PASNA, SANDD, Cav1.3, CCHL1A2, CACNL1A2, Voltage-dependent L-type calcium channel subunit alpha-1D, Calcium channel, L type, alpha-1 polypeptide, isoform 2, Voltage-gated calcium channel subunit alpha Cav1.3, CACNA1D

Background: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA).

Gen-ID: 776

UniProt: Q01668

Pathways: Sensory Perception of Sound