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LAG3 Antikörper (AA 210-260) (PE)

LAG3 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal PE
Produktnummer ABIN748518
  • Target Alle LAG3 Antikörper anzeigen
    LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
    Bindungsspezifität
    • 15
    • 14
    • 9
    • 7
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 210-260
    Reaktivität
    • 87
    • 38
    • 9
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 51
    • 35
    • 12
    • 4
    Kaninchen
    Klonalität
    • 52
    • 47
    • 1
    Polyklonal
    Konjugat
    • 53
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LAG3 Antikörper ist konjugiert mit PE
    Applikation
    • 68
    • 36
    • 33
    • 30
    • 25
    • 22
    • 15
    • 13
    • 13
    • 10
    • 10
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Human, Maus
    Homologie
    Rat,Cow,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Lymphocyte Activation Gene 3
    Isotyp
    IgG
    Top Product
    Discover our top product LAG3 Primärantikörper
  • Applikationshinweise
    FCM(1:20-100)
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Parodi, Battaglia, Kalli, Ferrera, Conteduca, Tardito, Stringara, Ivaldi, Negrini, Borgonovo, Simonato, Traverso, Carmignani, Fenoglio, Filaci: "CD39 is highly involved in mediating the suppression activity of tumor-infiltrating CD8+ T regulatory lymphocytes." in: Cancer immunology, immunotherapy : CII, Vol. 62, Issue 5, pp. 851-62, (2013) (PubMed).

  • Target
    LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
    Andere Bezeichnung
    Lymphocyte Activation Gene 3 (LAG3 Produkte)
    Hintergrund

    Synonyms: CD223, Lymphocyte activation gene 3 protein, LAG-3, Lag3

    Background: Lymphocyte-activation protein 3 (LAG-3), also known as CD223, belongs to the immunoglobulin superfamily and contains 4 extracellular Ig-like domains. LAG-3 binds to HLA class-II antigens and is involved in lymphocyte activation. It is found on the cell surface of activated NK and T-lymphocytes. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG-3 to CD4.

    Gen-ID
    297596
    UniProt
    Q5BK54
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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