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IL12RB1 Antikörper (AA 420-470)

IL12RB1 Reaktivität: Maus, Ratte WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN747863
  • Target Alle IL12RB1 Antikörper anzeigen
    IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
    Bindungsspezifität
    • 15
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 420-470
    Reaktivität
    • 44
    • 24
    • 23
    Maus, Ratte
    Wirt
    • 56
    • 7
    • 2
    • 1
    Kaninchen
    Klonalität
    • 59
    • 7
    Polyklonal
    Konjugat
    • 26
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL12RB1 Antikörper ist unkonjugiert
    Applikation
    • 43
    • 12
    • 12
    • 11
    • 11
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität (Details)
    Mouse
    Homologie
    Rat
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from mouse IL-12RB1
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:100-1000
    IHC-P 1:100-500
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Terayama, Yoshimoto, Hirai, Naito, Qu, Hatayama, Hayashi, Mitobe, Furusawa, Mizoguchi, Kezuka, Goto, Suyama, Moriyama, Sakabe, Itoh: "Contribution of IL-12/IL-35 common subunit p35 to maintaining the testicular immune privilege." in: PLoS ONE, Vol. 9, Issue 4, pp. e96120, (2014) (PubMed).

  • Target
    IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
    Andere Bezeichnung
    Il-12rb1/Cd212 (IL12RB1 Produkte)
    Synonyme
    Il12rb antikoerper, IL12RB1 antikoerper, IL-12R antikoerper, CD212 antikoerper, IL-12R-BETA1 antikoerper, IL12RB antikoerper, IL-12R[b] antikoerper, interleukin 12 receptor subunit beta 1 antikoerper, interleukin 12 receptor, beta 1 antikoerper, Il12rb1 antikoerper, IL12RB1 antikoerper
    Hintergrund

    Synonyms: CD212, IL-12R[b], Interleukin-12 receptor subunit beta-1, IL-12 receptor subunit beta-1, IL-12R subunit beta-1, IL-12R-beta-1, IL-12 receptor beta component, Il12rb1, Il12rb

    Background: Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.

    Gen-ID
    16161
    UniProt
    Q60837
    Pathways
    JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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