PTPN11 Antikörper (pTyr584) (Cy5.5)
Kurzübersicht für PTPN11 Antikörper (pTyr584) (Cy5.5) (ABIN745843)
Target
Alle PTPN11 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pTyr584
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Spezifität
- This phosphorylation site is homologous across the listed cross reactive species.
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Kreuzreaktivität
- Maus, Ratte
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Homologie
- Human,Horse,Chicken
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic phosphopeptide derived from human PTPN11 around the phosphorylation site of Tyr584
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Isotyp
- IgG
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anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (AA 514-593) antibody
PTPN11 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (AA 263-329) antibodyPTPN11 Reaktivität: Human IHC, ELISA, ICC, FACS Wirt: Maus Monoclonal 6D9 unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (C-Term) antibodyVerified PTPN11 Reaktivität: Human WB, ELISA, IF, FACS Wirt: Ziege Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (C-Term) antibodyKO Validated PTPN11 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (AA 69-99), (N-Term) antibodyPTPN11 Reaktivität: Human, Maus, Ratte WB, IHC, IF, ICC, FACS Wirt: Maus Monoclonal 2E6 unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (AA 526-551) antibodyPTPN11 Reaktivität: Human WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB21493 unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (AA 1-460) antibodyPTPN11 Reaktivität: Human WB, PLA Wirt: Maus Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) antibodyPTPN11 Reaktivität: Human WB, IF, IP Wirt: Kaninchen Monoclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (pTyr542) antibodyPTPN11 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (pTyr580) antibodyPTPN11 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
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Andere Bezeichnung
- PTPN11
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Hintergrund
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Synonyms: CFC, NS1, SHP2, BPTP3, PTP2C, PTP-1D, SH-PTP2, SH-PTP3, Tyrosine-protein phosphatase non-receptor type 11, Protein-tyrosine phosphatase 1D, Protein-tyrosine phosphatase 2C, PTP-2C, SHP-2, PTPN11, SHPTP2
Background: Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity.
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Gen-ID
- 5781
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UniProt
- Q06124
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Pathways
- JAK-STAT Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, Warburg Effekt
Target
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