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Phospholipase C gamma 1 Antikörper (pTyr783)

PLCG1 Reaktivität: Maus, Ratte WB, ELISA, IF (p), IHC (p), FACS, IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN744908
  • Target Alle Phospholipase C gamma 1 (PLCG1) Antikörper anzeigen
    Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))
    Bindungsspezifität
    • 41
    • 28
    • 14
    • 10
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr783
    Reaktivität
    • 157
    • 140
    • 130
    • 23
    • 10
    • 9
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Maus, Ratte
    Wirt
    • 159
    • 29
    Kaninchen
    Klonalität
    • 143
    • 45
    Polyklonal
    Konjugat
    • 87
    • 12
    • 12
    • 11
    • 10
    • 10
    • 9
    • 9
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Dieser Phospholipase C gamma 1 Antikörper ist unkonjugiert
    Applikation
    • 122
    • 52
    • 37
    • 33
    • 27
    • 26
    • 18
    • 18
    • 15
    • 15
    • 6
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    This phosphorylation site is homologous across the listed species.
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human,Dog,Pig,Horse,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human PLC gamma 1 around the phosphorylation site of Tyr783
    Isotyp
    IgG
    Top Product
    Discover our top product PLCG1 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Diaz-Flores, Goldschmidt, Depeille, Ng, Akutagawa, Krisman, Crone, Burgess, Williams, Houseman, Shokat, Sampath, Bollag, Roose, Braun, Shannon: "PLC-? and PI3K link cytokines to ERK activation in hematopoietic cells with normal and oncogenic Kras." in: Science signaling, Vol. 6, Issue 304, pp. ra105, (2013) (PubMed).

  • Target
    Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))
    Andere Bezeichnung
    PLC gamma 1 (PLCG1 Produkte)
    Synonyme
    NCKAP3 antikoerper, PLC-II antikoerper, PLC1 antikoerper, PLC148 antikoerper, PLCgamma1 antikoerper, plc1 antikoerper, nckap3 antikoerper, plc-ii antikoerper, plc148 antikoerper, plcgamma1 antikoerper, PPLCA antikoerper, AI894140 antikoerper, Cded antikoerper, Plc-1 antikoerper, Plc-gamma1 antikoerper, Plcg-1 antikoerper, fj46f04 antikoerper, wu:fj46f04 antikoerper, wu:fj57a05 antikoerper, phospholipase C gamma 1 antikoerper, phospholipase C gamma 1 L homeolog antikoerper, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 antikoerper, phospholipase C, gamma 1 antikoerper, PLCG1 antikoerper, plcg1.L antikoerper, LOC100633163 antikoerper, Plcg1 antikoerper, plcg1 antikoerper
    Hintergrund

    Synonyms: PLC1, NCKAP3, PLC-II, PLC148, PLCgamma1, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, PLC-148, Phosphoinositide phospholipase C-gamma-1, Phospholipase C-II, Phospholipase C-gamma-1, PLC-gamma-1, PLCG1

    Background: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.

    Gen-ID
    5335
    UniProt
    P19174
    Pathways
    RTK Signalweg, WNT Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, VEGFR1 Specific Signals, VEGF Signaling
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