IL13 Receptor alpha 1 Antikörper (AA 351-427)

Produktnummer ABIN740595

Produktdetails anti-IL13 Receptor alpha 1 Antikörper

Target: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Bindungsspezifität: AA 351-427

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL13 Receptor alpha 1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IL-13Ra1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu IL13 Receptor alpha 1

Target: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Andere Bezeichnung: IL-13Ra1 (IL13RA1 Produkte)

Synonyme: CD213A2 antikoerper, CT19 antikoerper, IL-13R antikoerper, IL13BP antikoerper, CD213A1 antikoerper, IL-13Ra antikoerper, NR4 antikoerper, AI882074 antikoerper, CD213a1 antikoerper, IL-13r[a] antikoerper, Il13ra antikoerper, IL13RA1 antikoerper, il-13ra1 antikoerper, si:ch211-150g2.2 antikoerper, interleukin 13 receptor subunit alpha 2 antikoerper, interleukin 13 receptor subunit alpha 1 antikoerper, interleukin 13 receptor, alpha 1 antikoerper, interleukin 13 receptor, alpha 1-like antikoerper, IL13RA2 antikoerper, IL13RA1 antikoerper, Il13ra1 antikoerper, il13ra1 antikoerper, LOC100360218 antikoerper

Hintergrund:

Synonyms: Interleukin-13 receptor subunit alpha-1, CD213A1, CD213A1 Antigen, IL 13R alpha 1, IL 13Ra, IL13R, IL13RA, IL13RA1, Interleukin 13 receptor alpha 1 chain, NR4, I13R1_HUMAN.

Background: The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.

Gen-ID: 3597

UniProt: P78552

Pathways: JAK-STAT Signalweg, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response