»
Antikörper
»
anti-Agrin (AGRN) Antikörper (RBITC)
Agrin (AGRN) Antikörper (RBITC)
| Antigen |
|
| Synonyme |
Agrin, AGR, FLJ45064, AGRN, AGRIN, agrn, wu:fb57e07 |
| Klonalität |
Polyklonal |
|
Wirt
|
|
|
Reaktivität
|
|
|
Konjugat
|
Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
|
|
Applikation
|
 Alternativen Durchflusszytometrie (FACS), Immunfluoreszenz (IF)
Immunfluoreszenz (IF) (22), Durchflusszytometrie (FACS) (17), Western Blot (WB) (8), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (5), ELISA (3), Immunpräzipitation (IP) (3), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunhistochemie (Paraffinschnitte) (IHC (p)) (2), Radioimmunoassay (RIA) (2), Enzyme Immunoassay (EIA) (1), Immunzytochemie (ICC) (1), Immunoelectron Microscopy (IEM) (1)
|
| Produktnummer |
ABIN738800 |
| Menge |
100 µg (1mg/1ml) |
| Preis |
256,41 € Zzgl. Versandkosten €20,00 und MWSt
|
| Lieferung nach |
|
| Verfügbarkeit |
Lieferung in 10 bis 15 Werktagen |
|
Weitere Bezeichnung
|
Agrin
|
|
Immunogen
|
Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human Agrin C-terminus
|
|
Format
|
Lyophilized
|
|
Wiederherstellung
|
Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)
|
|
Isotyp
|
IgG
|
|
Beschreibung
|
Synonym: AGRIN, Agrin proteoglycan, AGRN, FLJ45064, OTTHUMP00000044043.
|
|
Spezifität
|
Excitation / Emission Wavelengths: 495nm/519nm
|
|
Molekulargewicht
|
208kDa
|
|
Kommentare
|
Neuron marker
. Agrin is a neuronal aggregating factor that induces the aggregation of acetylcholine receptors and other postsynaptic proteins on muscle fibers and is crucial for the formation of the neuromuscular junction. Agrin is an essential extracellular matrix component which promotes clustering of nicotinic acetylcholine receptors (nAChRs) and other proteins during development at the neuromuscular junction. Agrin MuSK and Rapsyn are all essential components for AChR aggregation through an unknown mechanism. The C-terminal region of agrin is released into the medium interacts with receptors on the muscle surface and induces AChR aggregation. The central region contains two O-linked glycosylation sites and a domain homologous to domain III of laminin. The N-terminal region anchors agrin to the extracellular matrix via other basal membrane components. This region also contains a protease inhibitor domain and glycosaminoglycan attachment sites increasing the predicted MW from 200kDa to ~600kDa.
|
|
Applikationshinweise
|
Flow-Cyt (1:50-200), IF (1:50-200)
|
|
Konzentration
|
1mg/1ml
|
|
Reinigung
|
Antibodies are purified by protein A and peptide affinity chromatography.
|
|
Buffer
|
0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
|
|
Lagerung
|
Ship at room temperature. Store at -20°C
|
|
Forschungsgebiet
|
Neurologie
|
|
Beschränkungen
|
Nur für Forschungszwecke einsetzbar
|
Alternativen zu Antigen "Agrin (AGRN)", Typ "Antikörper" finden
|
Wirte
|
Kaninchen (19), Maus (10), Schaf (1)
|
|
Reaktivitäten
|
Ratte (Rattus) (28), Maus (26), Human (19)
|
|
Applikationen
|
Immunfluoreszenz (IF) (22), Durchflusszytometrie (FACS) (17), Western Blot (WB) (8), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (5), ELISA (3), Immunpräzipitation (IP) (3), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunhistochemie (Paraffinschnitte) (IHC (p)) (2), Radioimmunoassay (RIA) (2), Enzyme Immunoassay (EIA) (1), Immunzytochemie (ICC) (1), Immunoelectron Microscopy (IEM) (1)
|
|
Konjugate
|
Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
|
