5-HTT Antikörper (Gold)

Antigen: 5-HTT

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus), Rind (Kuh), Schaf, Huhn, Hund, Meerschweinchen, Schwein

Konjugat: Gold

Applikation: Immunoelectron Microscopy (IEM)

Produktnummer: ABIN735991

Produktbeschreibung

Immunogen: Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human 5-HTT C-terminus

Format: Lyophilized

Wiederherstellung: Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)

Isotyp: IgG

Beschreibung: Synonym: Serotoninreuptake transporter, sodium-dependent serotonin transporter, Solute carrier family 6 member 4, Slc6a4, 5-HTT, AI323329, Htt, MGC124313, MGC124314, Sert

Molekulargewicht: 69kDa

Kommentare:

This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants

such as amphetamines and cocaine

and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome

aggressive behavior in Alzheimer disease patients

and depression-susceptibility in people experiencing emotional trauma.

Anwendungen

Applikationshinweise: Electron Microscopy (1:100-500)

Konzentration: 1mg/1ml

Reinigung: Antibodies are purified by protein A and peptide affinity chromatography.

Buffer: 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

Lagerung: Ship at room temperature. Store at -20°C

Beschränkungen: Nur für Forschungszwecke einsetzbar