MMP12 Antikörper (AA 201-300)

Produktnummer ABIN735413

Produktdetails anti-MMP12 Antikörper

Target: MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))

Bindungsspezifität: AA 201-300

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus

Homologie: Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat MMP12

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-MMP12 Antikörper (ABIN735413)

Hashimoto, Zaima, Sekiguchi, Kugo, Miyamoto, Hoshino, Kawasaki, Sutoh, Usumi, Moriyama: "Dietary DNA Attenuates the Degradation of Elastin Fibers in the Aortic Wall in Nicotine-Administrated Mice." in: Journal of nutritional science and vitaminology, Vol. 64, Issue 4, pp. 271-276, (2019) (PubMed).

Kugo, Zaima, Onozato, Miyamoto, Hashimoto, Yanagimoto, Moriyama: "Suppressive effects of dietary EPA-rich fish oil on the degradation of elastin fibers in the aortic wall in nicotine-administered mice." in: Food & function, Vol. 8, Issue 8, pp. 2829-2835, (2017) (PubMed).

Details zu MMP12

Target: MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))

Andere Bezeichnung: MMP-12 (MMP12 Produkte)

Synonyme: MMP12 antikoerper, AV378681 antikoerper, Mmel antikoerper, Mme antikoerper, HME antikoerper, ME antikoerper, MME antikoerper, MMP-12 antikoerper, matrix metallopeptidase 12 antikoerper, MMP12 antikoerper, Mmp12 antikoerper

Hintergrund:

Synonyms: Mme, Macrophage metalloelastase, Matrix metalloproteinase-12, MMP-12, Mmp12, Mmel

Background: May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3 (By similarity).

Gen-ID: 117033

UniProt: Q63341