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MASP1 Antikörper (AA 20-120)

MASP1 Reaktivität: Human, Maus, Ratte WB, ELISA, IF (p), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN733508
  • Target Alle MASP1 Antikörper anzeigen
    MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
    Bindungsspezifität
    • 14
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-120
    Reaktivität
    • 48
    • 19
    • 18
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 43
    • 5
    • 1
    Kaninchen
    Klonalität
    • 45
    • 4
    Polyklonal
    Konjugat
    • 21
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MASP1 Antikörper ist unkonjugiert
    Applikation
    • 44
    • 22
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Dog,Cow,Pig,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MASP
    Isotyp
    IgG
    Top Product
    Discover our top product MASP1 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
    Andere Bezeichnung
    MASP (MASP1 Produkte)
    Synonyme
    AW048060 antikoerper, CCPII antikoerper, Crarf antikoerper, Masp1/3 antikoerper, 3MC1 antikoerper, CRARF antikoerper, CRARF1 antikoerper, MAP1 antikoerper, MASP antikoerper, MASP3 antikoerper, MAp44 antikoerper, PRSS5 antikoerper, RaRF antikoerper, mannan-binding lectin serine peptidase 1 antikoerper, mannan binding lectin serine peptidase 1 antikoerper, Masp1 antikoerper, MASP1 antikoerper
    Hintergrund

    Synonyms: 3MC1, MAP1, MASP, RaRF, CRARF, MASP3, MAp44, PRSS5, CRARF1, Mannan-binding lectin serine protease 1, Complement factor MASP-3, Complement-activating component of Ra-reactive factor, Mannose-binding lectin-associated serine protease 1, MASP-1, Mannose-binding protein-associated serine protease, Ra-reactive factor serine protease p100, Serine protease 5, MASP1

    Background: Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5.

    Gen-ID
    5648
    UniProt
    P48740
    Pathways
    Komplementsystem
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