MASP1 Antikörper (Mannan-Binding Lectin serine Peptidase 1 (C4/C2 Activating Component of Ra-Reactive Factor))

Details for Product anti-MASP1 Antibody No. ABIN733508, Anbieter: Anmelden zum Anzeigen
Antigen
  • AW048060
  • CCPII
  • Crarf
  • Masp1/3
  • 3MC1
  • CRARF
  • CRARF1
  • MAP1
  • MASP
  • MASP3
  • MAp44
  • PRSS5
  • RaRF
  • mannan-binding lectin serine peptidase 1
  • mannan binding lectin serine peptidase 1
  • Masp1
  • MASP1
Reaktivität
Human, Maus, Ratte (Rattus)
74
23
23
2
2
1
1
1
1
Wirt
Kaninchen
52
21
1
Klonalität
Polyklonal
Konjugat
Dieser MASP1 Antikörper ist unkonjugiert
4
4
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
60
19
12
4
4
3
3
2
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen KLH conjugated synthetic peptide derived from human MASP
Isotyp IgG
Reinigung Purified by Protein A.
Andere Bezeichnung Masp (MASP1 Antibody Abstract)
Hintergrund

Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5.

Subcellular location: Secreted

Synonyms: 3MC1, MAP1, MASP, RaRF, CRARF, MASP3, MAp44, PRSS5, CRARF1, Mannan-binding lectin serine protease 1, Complement factor MASP-3, Complement-activating component of Ra-reactive factor, Mannose-binding lectin-associated serine protease 1, MASP-1, Mannose-binding protein-associated serine protease, Ra-reactive factor serine protease p100, Serine protease 5, MASP1

Gen-ID 5648
UniProt P48740
Pathways Komplementsystem
Applikationshinweise WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Mannan-Binding Lectin serine Peptidase 1 (C4/C2 Activating Component of Ra-Reactive Factor) (MASP1) antibody (ABIN733508) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti- MASP Pol...
Western Blotting (WB) image for anti-Mannan-Binding Lectin serine Peptidase 1 (C4/C2 Activating Component of Ra-Reactive Factor) (MASP1) antibody (ABIN733508) Rat brain lysates probed with Rabbit Anti-MASP Polyclonal Antibody at 1:5000 90min i...
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