ABCB5 Antikörper (AA 841-883)

Produktnummer ABIN731933

Produktdetails anti-ABCB5 Antikörper

Target: ABCB5 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 5 (ABCB5))

Bindungsspezifität: AA 841-883

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABCB5 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ABCB5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-ABCB5 Antikörper (ABIN731933)

Kaushik, Venugopal, Ramamoorthy, Standing, Subramaniam, Umar, Jensen, Anant, Mammen: "Honokiol inhibits melanoma stem cells by targeting notch signaling." in: Molecular carcinogenesis, (2014) (PubMed).

Details zu ABCB5

Target: ABCB5 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 5 (ABCB5))

Andere Bezeichnung: ABCB5 (ABCB5 Produkte)

Synonyme: ABCB5alpha antikoerper, ABCB5beta antikoerper, EST422562 antikoerper, 9230106F14Rik antikoerper, RGD1566342 antikoerper, ABCB5 antikoerper, mdr1 antikoerper, im:7158730 antikoerper, wu:fc18f02 antikoerper, wu:fi81f06 antikoerper, ATP binding cassette subfamily B member 5 antikoerper, ATP-binding cassette, sub-family B (MDR/TAP), member 5 antikoerper, ATP-binding cassette sub-family B member 5 antikoerper, ABCB5 antikoerper, Abcb5 antikoerper, abcb5 antikoerper, TGME49_249820 antikoerper, PAAG_04387 antikoerper, VDBG_00160 antikoerper, VDBG_02292 antikoerper

Hintergrund:

Synonyms: ABCB5beta, EST422562, ABCB5alpha, ATP-binding cassette sub-family B member 5, ABCB5 P-gp, P-glycoprotein ABCB5, ABCB5

Background: Drug efflux transporter present in a number of stem cells that acts as a regulator of cellular differentiation. Able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair.

Gen-ID: 340273

UniProt: Q2M3G0