Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

IRS2 Antikörper (AA 501-600)

IRS2 Reaktivität: Human, Maus, Ratte ELISA, WB, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN725840
  • Target Alle IRS2 Antikörper anzeigen
    IRS2 (Insulin Receptor Substrate 2 (IRS2))
    Bindungsspezifität
    • 16
    • 15
    • 12
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 501-600
    Reaktivität
    • 74
    • 46
    • 32
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 74
    Kaninchen
    Klonalität
    • 74
    Polyklonal
    Konjugat
    • 25
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Dieser IRS2 Antikörper ist unkonjugiert
    Applikation
    • 38
    • 36
    • 30
    • 26
    • 20
    • 11
    • 9
    • 9
    • 8
    • 5
    • 5
    • 3
    • 2
    • 1
    ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human IRS-2
    Isotyp
    IgG
    Top Product
    Discover our top product IRS2 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Wang, Wang, Zhang, Lin, Liu, Xiao, Xiao, Wang: "Defective insulin signaling and the protective effects of dimethyldiguanide during follicular development in the ovaries of polycystic ovary syndrome." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 8164-8170, (2017) (PubMed).

    Ling, Xie, Li, Liu, Cao, Yang, Wang, Hu, Xu, Zheng: "Donor Graft MicroRNAs: A Newly Identified Player in the Development of New-onset Diabetes After Liver Transplantation." in: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, Vol. 17, Issue 1, pp. 255-264, (2016) (PubMed).

  • Target
    IRS2 (Insulin Receptor Substrate 2 (IRS2))
    Andere Bezeichnung
    IRS-2 (IRS2 Produkte)
    Synonyme
    IRS2 antikoerper, si:dkeyp-24d6.1 antikoerper, IRS-2 antikoerper, 4PS antikoerper, Irs-2 antikoerper, insulin receptor substrate 2 antikoerper, insulin receptor substrate 2a antikoerper, insulin receptor substrate 2b antikoerper, IRS2 antikoerper, irs2a antikoerper, irs2b antikoerper, Irs2 antikoerper
    Hintergrund

    Synonyms: IRS-2, Insulin receptor substrate 2, IRS2

    Background: The family of insulin receptor substrates (IRSs) has been reported to play important roles for signal transduction of various hormones. Four members of the IRS family have been described. Each IRS is believed to have different functions, however, the distinct physiological roles of each IRS are unclear. Summary: This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.

    Gen-ID
    8660
    UniProt
    Q9Y4H2
    Pathways
    Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
Sie sind hier:
Kundenservice