Calcitonin-Related Polypeptide alpha (CALCA) Antikörper

Antigen: Calcitonin-Related Polypeptide alpha (CALCA)

Synonyme: CALCA, CALC3, MGC152154, CT, KC, CGRP, CALC1, CGRP1, CGRP-I, MGC126648, CFP1, CGBP, SPP1, PCCX1, PHF18, hCGBP, HsT2645, 2410002I16Rik, 5830420C16Rik, CALC, calcitonin, calca, ci-ct

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Hund

Applikation: Western Blot (WB), ELISA, Immunpräzipitation (IP), Immunhistochemie (Paraffinschnitte) (IHC (p)), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)), Durchflusszytometrie (FACS), Immunfluoreszenz (IF)

Produktnummer: ABIN724370

Produktbeschreibung

Weitere Bezeichnung: Calcitonin

Immunogen: Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human Calcitonin C-terminus

Format: Lyophilized

Wiederherstellung: Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Synonym: Alpha CGRP, CALC 1, CALC A, CALC1, CALCA, Calcitonin related polypeptide alpha, CGRP 1, CGRP, CGRP I, CGRP1, CGRPI, CT, Katacalcin, KC, MGC126648.

Molekulargewicht: 15kDa

Kommentare:

Calcitonin is a 32 amino acid peptide hormone synthesized by the parafollicular cells of the thyroid. It causes a rapid

but short lived

reduction in serum calcium and phosphate by promoting the incorporation of those ions in the bones. This effect is opposite to that of parathyroid hormone. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varying degrees of calcitonin activity.

Anwendungen

Applikationshinweise: WB (1:100-500), ELISA (1:500-1000), IP (1:20-100), IHC-P (1:100-500), IHC-F (1:100-500), Flow-Cyt (1:20-100), IF (1:50-200)

Konzentration: 1mg/1ml

Reinigung: affinity purified by Protein A

Buffer: 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

Lagerung: Ship at room temperature. Store at -20°C

Forschungsgebiet: Krebs, Wachstumsfaktoren, Hormone, Zytoskelett, Mikrofilamente, Angeborene Immunität, Chemokine

Beschränkungen: Nur für Forschungszwecke einsetzbar