Sodium Channel, Voltage-Gated, Type I, beta (SCN1B) Antikörper (Biotin)

Antigen: Sodium Channel, Voltage-Gated, Type I, beta (SCN1B)

Synonyme: GEFSP1

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus)

Konjugat: Biotin

Applikation: Western Blot (WB), ELISA, Immunpräzipitation (IP), Immunhistochemie (Paraffinschnitte) (IHC (p)), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)), Durchflusszytometrie (FACS), Immunfluoreszenz (IF)

Produktnummer: ABIN719968

Produktbeschreibung

Weitere Bezeichnung: SCN1B

Immunogen: Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from hu SCN1B

Format: Lyophilized

Wiederherstellung: Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)

Isotyp: IgG

Beschreibung: Synonym: GEFSP1, SCN1B, SCN1B_HUMAN, sodium channel beta 1 subunit, Sodium channel subunit beta 1, Sodium channel subunit beta-1, Sodium channel voltage gated type I beta.

Molekulargewicht: 25kDa

Kommentare:

Crucial in the assembly

expression

and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-1 can modulate multiple alpha subunit isoforms from brain

skeletal muscle

and heart. Its association with neurofascin may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.. Tissue specificity

_x000D_ Abundantly expressed in skeletal muscle

heart and brain.

Anwendungen

Applikationshinweise: WB (1:100-500), ELISA (1:500-1000), IP (1:20-100), IHC-P (1:100-500), IHC-F (1:100-500), Flow-Cyt (1:20-100), IF (1:50-200)

Konzentration: 1mg/1ml

Reinigung: Antibodies are purified by protein A and peptide affinity chromatography.

Buffer: Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

Lagerung: Ship at room temperature. Store at -20°C

Forschungsgebiet: Signaltransduktion, Metabolismus

Beschränkungen: Nur für Forschungszwecke einsetzbar