ADAMTS10 Antikörper (AA 851-950) (Cy3)

Produktnummer ABIN718499

Der Kaninchen Polyklonal anti-ADAMTS10 Antikörper wird verwendet zum Nachweis von ADAMTS10 in Proben von Human. Er wurde validiert für IF (cc) und IF (p).

Kurzübersicht für ADAMTS10 Antikörper (AA 851-950) (Cy3) (ABIN718499)

Target: ADAMTS10 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 10 (ADAMTS10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADAMTS10 Antikörper ist konjugiert mit Cy3

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-ADAMTS10 Antikörper (Cy3)

Bindungsspezifität: AA 851-950

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ADAMTS10

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ADAMTS10

Target: ADAMTS10 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 10 (ADAMTS10))

Andere Bezeichnung: ADAMTS10

Hintergrund:

Synonyms: A disintegrin and metalloproteinase with thrombospondin mots 10, A disintegrin like and metalloprotease reprolysin type with thrombospondin type 1 mot, 10, ADAM metallopeptidase with thrombospondin type 1 mot 10, ADAM TS10, EC 3.4.24, WMS, ATS10_HUMAN.

Background: ADAMTS10 is a member of the ADAMs family of proteinases with Thrombospondin motifs. The catalytic site of ADAMTS10 is typical of the metalloproteinase catalytic domains, with an HExxHxxxxxH sequence, perhaps giving these enzymes some shared specificity. ADAMTS10 is closest in homology to ADAMTS6, sharing 53 % overall identity. Functional mutations in ADAMTS10 have been linked to Weill Marchesani syndrome, a connective tissue disorder marked by fibrillin 1 misprocessing. ADAMTS10 has also been reported to be over expressed in breast cancer tissues and cell lines.

Gen-ID: 81794