Jagged 2 (JAG2) Antikörper (RBITC)

Antigen: Jagged 2 (JAG2)

Synonyme: HJ2, SER2, sm, Serh, D12Ggc2e, mJagged2-1, serB, zgc:152855, JAG2

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Konjugat: RBITC

Applikation: Durchflusszytometrie (FACS), Immunfluoreszenz (IF)

Produktnummer: ABIN705805

Produktbeschreibung

Weitere Bezeichnung: Jagged 2

Immunogen: Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human Jagged 2

Format: Lyophilized

Wiederherstellung: Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)

Isotyp: IgG

Beschreibung: Synonym: D12Ggc2e, HJ 2, HJ2, JAG 2, JAG2, Jagged 2 precursor, Jagged2, Syndactylism.

Spezifität: Excitation / Emission Wavelengths: 495nm/519nm

Molekulargewicht: 120-135kDa

Kommentare:

Jagged 2 is a Notch ligand involved in the mediation of Notch signaling. Jagged 2 is expressed in heart

placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain

lung

liver and kidney. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. Jagged 2 is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for Jagged 2.

Anwendungen

Applikationshinweise: Flow-Cyt (1:50-200), IF (1:50-200)

Konzentration: 1mg/1ml

Reinigung: Antibodies are purified by protein A and peptide affinity chromatography.

Buffer: 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

Lagerung: Ship at room temperature. Store at -20°C

Beschränkungen: Nur für Forschungszwecke einsetzbar