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serine/threonine Kinase 17b (STK17B) Antikörper (PE,Cy5)

Antigen

serine/threonine Kinase 17b (STK17B)

Synonyme DRAK2, Drak2, MGC65989, zgc:65989, STK17B, MGC134048
Klonalität Polyklonal
Wirt
Alternativen

Kaninchen

Reaktivität
Alternativen

Human, Ratte (Rattus), Maus

Konjugat
Alternativen PE,Cy5
Applikation
Alternativen Durchflusszytometrie (FACS), Immunfluoreszenz (IF)
Produktnummer ABIN704093
Menge 100 µg  (1mg/1ml)
Preis 307,69 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 10 bis 15 Werktagen

Produktbeschreibung

Weitere Bezeichnung DRAK2
Immunogen Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human DRAK2
Format Lyophilized
Wiederherstellung Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)
Isotyp IgG
Beschreibung Synonym: DAP kinase related apoptosis inducing protein, DAP kinase related apoptosis inducing protein kinase 2, Death associated protein kinase related 2, DRAK 2, Serine/threonine kinase 17b (apoptosis inducing), Serine/threonine kinase 17b, Serine/threonine protein kinase 17B, STK17B.
Spezifität Excitation / Emission Wavelengths: 650nm/670nm
Molekulargewicht 43-45kDa
Kommentare

Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases

such as ASK1 and RIP

are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase related apoptosis inducing protein kinases). DRAKs contain an N terminal kinase domain and a C terminal regulation domain. Overexpression of DRAK2 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases

and they represent a novel family of serine/threonine kinases

which mediates apoptosis through their catalytic activities. DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.

Anwendungen

Applikationshinweise Flow-Cyt (1:50-200), IF (1:50-200)
Konzentration 1mg/1ml
Reinigung Antibodies are purified by protein A and peptide affinity chromatography.
Buffer 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
Lagerung Ship at room temperature. Store at -20°C
Forschungsgebiet Signaltransduktion, Apoptose/Nekrose
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "serine/threonine Kinase 17b (STK17B)", Typ "Antikörper" finden
Wirte Kaninchen (42), Ziege (7), Maus (3)
Reaktivitäten Human (48), Maus (18), Ratte (Rattus) (17), Rind (Kuh) (3), Pferd (3), Schwein (3), Kaninchen (3), Hund (1)
Applikationen Western Blot (WB) (26), Immunfluoreszenz (IF) (24), Durchflusszytometrie (FACS) (17), Immunhistochemie (Paraffinschnitte) (IHC (p)) (16), ELISA (7), Enzyme Immunoassay (EIA) (4), Immunpräzipitation (IP) (4), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (2), Dot Blot (Dot) (1), Immunzytochemie (ICC) (1), Immunoelectron Microscopy (IEM) (1), Immunhistochemie (IHC) (1)
Konjugate Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitope C-Term (6)