»
Antikörper
»
anti-serine/threonine Kinase 17b (STK17B) Antikörper (PE)
serine/threonine Kinase 17b (STK17B) Antikörper (PE)
| Antigen |
|
| Synonyme |
DRAK2, Drak2, MGC65989, zgc:65989, STK17B, MGC134048 |
| Klonalität |
Polyklonal |
|
Wirt
|
|
|
Reaktivität
|
|
|
Konjugat
|
Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
|
|
Applikation
|
 Alternativen Durchflusszytometrie (FACS), Immunfluoreszenz (IF)
Western Blot (WB) (26), Immunfluoreszenz (IF) (24), Durchflusszytometrie (FACS) (17), Immunhistochemie (Paraffinschnitte) (IHC (p)) (16), ELISA (7), Enzyme Immunoassay (EIA) (4), Immunpräzipitation (IP) (4), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (2), Dot Blot (Dot) (1), Immunzytochemie (ICC) (1), Immunoelectron Microscopy (IEM) (1), Immunhistochemie (IHC) (1)
|
| Produktnummer |
ABIN704091 |
| Menge |
100 µg (1mg/1ml) |
| Preis |
290,60 € Zzgl. Versandkosten €20,00 und MWSt
|
| Lieferung nach |
|
| Verfügbarkeit |
Lieferung in 10 bis 15 Werktagen |
|
Weitere Bezeichnung
|
DRAK2
|
|
Immunogen
|
Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human DRAK2
|
|
Format
|
Lyophilized
|
|
Wiederherstellung
|
Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)
|
|
Isotyp
|
IgG
|
|
Beschreibung
|
Synonym: DAP kinase related apoptosis inducing protein, DAP kinase related apoptosis inducing protein kinase 2, Death associated protein kinase related 2, DRAK 2, Serine/threonine kinase 17b (apoptosis inducing), Serine/threonine kinase 17b, Serine/threonine protein kinase 17B, STK17B.
|
|
Spezifität
|
Excitation / Emission Wavelengths: 565nm/578nm
|
|
Molekulargewicht
|
43-45kDa
|
|
Kommentare
|
Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases such as ASK1 and RIP are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase related apoptosis inducing protein kinases). DRAKs contain an N terminal kinase domain and a C terminal regulation domain. Overexpression of DRAK2 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases and they represent a novel family of serine/threonine kinases which mediates apoptosis through their catalytic activities. DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.
|
|
Applikationshinweise
|
Flow-Cyt (1:50-200), IF (1:50-200)
|
|
Konzentration
|
1mg/1ml
|
|
Reinigung
|
Antibodies are purified by protein A and peptide affinity chromatography.
|
|
Buffer
|
0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
|
|
Lagerung
|
Ship at room temperature. Store at -20°C
|
|
Forschungsgebiet
|
Signaltransduktion, Apoptose/Nekrose
|
|
Beschränkungen
|
Nur für Forschungszwecke einsetzbar
|
Alternativen zu Antigen "serine/threonine Kinase 17b (STK17B)", Typ "Antikörper" finden
|
Wirte
|
Kaninchen (42), Ziege (7), Maus (3)
|
|
Reaktivitäten
|
Human (48), Maus (18), Ratte (Rattus) (17), Rind (Kuh) (3), Pferd (3), Schwein (3), Kaninchen (3), Hund (1)
|
|
Applikationen
|
Western Blot (WB) (26), Immunfluoreszenz (IF) (24), Durchflusszytometrie (FACS) (17), Immunhistochemie (Paraffinschnitte) (IHC (p)) (16), ELISA (7), Enzyme Immunoassay (EIA) (4), Immunpräzipitation (IP) (4), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (2), Dot Blot (Dot) (1), Immunzytochemie (ICC) (1), Immunoelectron Microscopy (IEM) (1), Immunhistochemie (IHC) (1)
|
|
Konjugate
|
Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
|
|
Epitope
|
C-Term (6)
|
