BRN3A Antikörper (Gold)

Antigen: BRN3A

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Ratte (Rattus), Maus

Konjugat: Gold

Applikation: Immunoelectron Microscopy (IEM)

Produktnummer: ABIN702408

Produktbeschreibung

Immunogen: Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human BRN3A

Format: Lyophilized

Wiederherstellung: Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)

Isotyp: IgG

Beschreibung: Synonym: Brain specific homeobox/POU domain protein 3A, Brn 3.0, BRN 3A, Brn3, Homeobox/POU domain protein RDC 1, Homeobox/POU domain protein RDC1, Oct T1, OctT1, POU Domain Class 4 Transcription Factor 1, POU4F1, RDC 1, RDC1.

Molekulargewicht: 43kDa

Kommentare:

Brn3a (Brain-specific homeobox/POU domain protein 3A) is a transcription factor specifically expressed in cells of the developing mammalian nervous system. Brn3a is implicated in the regulation of specific gene expression within a subset of neuronal lineages and may play a role in determining or maintaining the identities of a small subset of visual system neurons. Brn3a is expressed in enbryonic brain

peripheral sensory nervous system and retina. In the adult nervous system Brn3a is primarily found in the CNS: medial habenula

superficial gray of the superior colliculus

red nucleus

mesencephalic nucleus of the trigeminal ganglion

nucleus ambiguus

inferior olivary nucleus and peripheral sensory ganglia.

Anwendungen

Applikationshinweise: Electron Microscopy (1:100-500)

Konzentration: 1mg/1ml

Reinigung: Antibodies are purified by protein A and peptide affinity chromatography.

Buffer: 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

Lagerung: Ship at room temperature. Store at -20°C

Forschungsgebiet: Chromatin und nukleäre Signaltransduktion, Transkriptionsfaktoren, Neuronale Stammzellmarker

Beschränkungen: Nur für Forschungszwecke einsetzbar