Histone H1 Antikörper (PE)

Antigen: Histone H1

Synonyme: H1c, H1.2, H1f2, His1a, H1var1, MGC107646, 0610008C09Rik, LOC692942, HISTONE H1, HON4

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus), Kaninchen, Pferd, Schwein, Rind (Kuh), Hund

Konjugat: PE

Applikation: Durchflusszytometrie (FACS), Immunfluoreszenz (IF)

Produktnummer: ABIN686207

Produktbeschreibung

Immunogen: Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human Histone H1 C-terminus

Format: Lyophilized

Wiederherstellung: Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)

Isotyp: IgG

Beschreibung: Synonym: H1oo, Oocyte specific linker histone H1, dJ221C16.2, dJ221C16.5, DmeH1, H1 0 histone, H1, H1 histone family member 0, H1 histone family member 1, H1 histone family member 3, H1 histone family member 5, H1 histone family member N testis specific, H1 histone family member O oocyte specific, H1 histone family member X, H1(0), H1.1, H1.2, H1.3, H1.4, H1.5, H10, H1A, H1f0, H1F0 protein, H1F1, H1F2, H1F3, H1F4, H1F5, H1FNT, H1FOO, H1FOO protein, H1FT, H1FV, H1FX, H1t, H1T2, H1X, HANP1, His1, HisC, HIST1, HIST1H1A, HIST1H1B, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1T, Histone 1 H1a, Histone 1 H1b, Histone 1 H1c, Histone 1 H1d, Histone 1 H1e, Histone 1 H1t, Histone, Histone H1, Histone H1.0, Histone H1.1, Histone H1.2, Histone H1.3, Histone H1.4, Histone H1.5, Histone H1x, MGC116819, MGC126630, MGC126632, MGC126642, MGC138176, MGC138345, MGC15959, MGC3992, MGC50807, MGC5241, MGC8350, Oocyte specific histone H1, osH1, Testicular H1 histone.

Spezifität: Excitation / Emission Wavelengths: 565nm/578nm

Molekulargewicht: 22kDa

Kommentare:

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A

H2B

H3

and H4) form an octamer

around which approximately 146 bp of DNA is wrapped in repeating units

called nucleosomes. The linker histone

H1

interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Anwendungen

Applikationshinweise: Flow-Cyt (1:50-200), IF (1:50-200)

Konzentration: 1mg/1ml

Reinigung: Antibodies are purified by protein A and peptide affinity chromatography.

Buffer: 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

Lagerung: Ship at room temperature. Store at -20°C

Forschungsgebiet: Chromatin und nukleäre Signaltransduktion, DNS/RNS, Transkriptionsfaktoren

Beschränkungen: Nur für Forschungszwecke einsetzbar