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TRPM2 Antikörper (AA 951-1050)

TRPM2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN681223
  • Target Alle TRPM2 Antikörper anzeigen
    TRPM2 (Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2))
    Bindungsspezifität
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 951-1050
    Reaktivität
    • 30
    • 20
    • 17
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 44
    • 1
    Kaninchen
    Klonalität
    • 45
    Polyklonal
    Konjugat
    • 23
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TRPM2 Antikörper ist unkonjugiert
    Applikation
    • 30
    • 22
    • 11
    • 11
    • 9
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human TRPM2
    Isotyp
    IgG
    Top Product
    Discover our top product TRPM2 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    TRPM2 (Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2))
    Andere Bezeichnung
    TRPM2 (TRPM2 Produkte)
    Synonyme
    EREG1 antikoerper, KNP3 antikoerper, LTRPC2 antikoerper, NUDT9H antikoerper, NUDT9L1 antikoerper, TRPC7 antikoerper, Trpm2-predicted antikoerper, TRPM2 antikoerper, si:ch73-263b18.1 antikoerper, 9830168K16Rik antikoerper, C79133 antikoerper, Trp7 antikoerper, Trrp7 antikoerper, transient receptor potential cation channel subfamily M member 2 antikoerper, transient receptor potential cation channel, subfamily M, member 2 antikoerper, transient receptor potential cation channel subfamily C member 7 antikoerper, TRPM2 antikoerper, Trpm2 antikoerper, trpm2 antikoerper, TRPC7 antikoerper
    Hintergrund

    Synonyms: KNP3, EREG1, TRPC7, LTRPC2, NUDT9H, NUDT9L1, Transient receptor potential cation channel subfamily M member 2, Estrogen-responsive element-associated gene 1 protein, Long transient receptor potential channel 2, LTrpC-2, Transient receptor potential channel 7, TRPM2

    Background: Nonselective, voltage-independent cation channel mediating sodium and calcium ion influx in response to oxidative stress. Extracellular calcium passes through the channel and acts from the intracellular side as a positive regulator in channel activation. Activated by ADP-ribose, nicotinamide adenine dinucleotide (NAD(+)), reactive nitrogen species and arachidonic acid. Inactivated by intracellular ATP. Confers susceptibility to cell death following oxidative stress. Isoform 2 does not seem to be regulated by ADPR. Has ADP-ribose pyrophosphatase activity.

    Gen-ID
    7226
    UniProt
    O94759
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