Kallikrein 7 Antikörper (AA 101-200)

Produktnummer ABIN676028

Produktdetails anti-Kallikrein 7 Antikörper

Target: Kallikrein 7 (KLK7)

Bindungsspezifität: AA 101-200

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Kallikrein 7 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KLK7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Kallikrein 7 Antikörper (ABIN676028)

Yamamoto, Yamamoto, Yamada, Hasegawa, Hongo, Oda, Amizuka: "Hertwig's epithelial root sheath cell behavior during initial acellular cementogenesis in rat molars." in: Histochemistry and cell biology, Vol. 142, Issue 5, pp. 489-96, (2014) (PubMed).

Details zu Kallikrein 7

Target: Kallikrein 7 (KLK7)

Andere Bezeichnung: KLK7 (KLK7 Produkte)

Synonyme: Prss6 antikoerper, SCCE antikoerper, PRSS6 antikoerper, hK7 antikoerper, kallikrein related-peptidase 7 (chymotryptic, stratum corneum) antikoerper, kallikrein-related peptidase 7 antikoerper, kallikrein related peptidase 7 antikoerper, Klk7 antikoerper, KLK7 antikoerper

Hintergrund:

Synonyms: hK7, SCCE, PRSS6, Kallikrein-7, Serine protease 6, Stratum corneum chymotryptic enzyme, hSCCE, KLK7

Background: May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr-|-Gln-15' and insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines.

Gen-ID: 5650

UniProt: P49862

Pathways: Komplementsystem