Aromatase Antikörper (AA 41-140) (FITC)

Produktnummer ABIN674536

Produktdetails anti-Aromatase Antikörper (FITC)

Target: Aromatase (CYP19A1) (Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1))

Bindungsspezifität: AA 41-140

Reaktivität: Human, Ratte, Maus, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aromatase Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Rind (Kuh), Human, Maus, Ratte

Homologie: Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Aromatase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Aromatase Antikörper (FITC) (ABIN674536)

Lan, Chen, Jan, Chen, Ho: "Differentiation of human embryonic stem cells into functional ovarian granulosa-like cells." in: The Journal of clinical endocrinology and metabolism, Vol. 98, Issue 9, pp. 3713-23, (2013) (PubMed).

Details zu Aromatase

Target: Aromatase (CYP19A1) (Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1))

Andere Bezeichnung: Aromatase (CYP19A1 Produkte)

Synonyme: ARO antikoerper, ARO1 antikoerper, CPV1 antikoerper, CYAR antikoerper, CYP19 antikoerper, CYPXIX antikoerper, P-450AROM antikoerper, Aromatase antikoerper, Cyp19 antikoerper, Cyp19a antikoerper, p450arom antikoerper, P450 arom antikoerper, aro antikoerper, cyp19 antikoerper, cyp19a antikoerper, p450arom-A antikoerper, P450AROM antikoerper, Ar antikoerper, ArKO antikoerper, Int-5 antikoerper, Int5 antikoerper, CYP19P1 antikoerper, CYP19A1 antikoerper, CYP19a1 antikoerper, P450aromA antikoerper, ar1 antikoerper, cypXIX antikoerper, etID309862.18 antikoerper, zgc:136541 antikoerper, AroB antikoerper, CYP19a2 antikoerper, P450aromB antikoerper, cyp19b antikoerper, zgc:92614 antikoerper, cyp19a1 antikoerper, cytochrome P450 family 19 subfamily A member 1 antikoerper, cytochrome P450, family 19, subfamily a, polypeptide 1 antikoerper, cytochrome P450 family 19 subfamily A member 1 L homeolog antikoerper, aromatase antikoerper, cytochrome P450 aromatase antikoerper, cytochrome P450, family 19, subfamily A, polypeptide 1 antikoerper, cytochrome P450 19A1 antikoerper, cytochrome P450, family 17, subfamily A, polypeptide 1 antikoerper, cytochrome P450, family 19 antikoerper, cytochrome P450, family 19, subfamily A, polypeptide 1a antikoerper, cytochrome P450, family 19, subfamily A, polypeptide 1b antikoerper, cytochrome P450 19A1-like antikoerper, CYP19A1 antikoerper, Cyp19a1 antikoerper, cyp19a1.L antikoerper, SAV_2383 antikoerper, pfcyp19b-tstr antikoerper, CYP19 antikoerper, cyp19a1a antikoerper, cyp19a1b antikoerper, LOC101174651 antikoerper

Hintergrund:

Synonyms: ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-45AROM, Aromatase, Cytochrome P-45AROM, Cytochrome P45 19A1, Estrogen synthase, CYP19A1

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity, the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. Belongs to the cytochrome P450 family.

Gen-ID: 1588

UniProt: P11511

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis