BAK1 Antikörper (AA 21-120)

Produktnummer ABIN674409

Produktdetails anti-BAK1 Antikörper

Target: BAK1 (BCL2-Antagonist/killer 1 (BAK1))

Bindungsspezifität: AA 21-120

Reaktivität: Human, Maus, Ratte, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Huhn, Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse BAK

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-BAK1 Antikörper (ABIN674409)

Yang, Pei, Zhang, Liao, Yu, Qiao, Han, Li, Hu, Guo, Pan, Tang: "Copper induces oxidative stress and apoptosis through mitochondria-mediated pathway in chicken hepatocytes." in: Toxicology in vitro : an international journal published in association with BIBRA, Vol. 54, pp. 310-316, (2019) (PubMed).

Huang, Chao, Lee, Lu, Cheng, Yang, Wang, Chang, Huang: "Paraquat Induces Cell Death Through Impairing Mitochondrial Membrane Permeability." in: Molecular neurobiology, (2015) (PubMed).

Zhu, Wang, Liang, Wang, Zhang, Li, Ying: "Regulation of cell transformation by Rb-controlled redox homeostasis." in: PLoS ONE, Vol. 9, Issue 7, pp. e102582, (2014) (PubMed).

Details zu BAK1

Target: BAK1 (BCL2-Antagonist/killer 1 (BAK1))

Andere Bezeichnung: BAK (BAK1 Produkte)

Synonyme: BAK antikoerper, BAK-LIKE antikoerper, BCL2L7 antikoerper, CDN1 antikoerper, Bak antikoerper, N-BAK1 antikoerper, N-Bak antikoerper, Bak1 antikoerper, bak antikoerper, bak1 antikoerper, BCL2 antagonist/killer 1 antikoerper, BCL2-antagonist/killer 1 antikoerper, BCL2 antagonist/killer 1 L homeolog antikoerper, BAK1 antikoerper, Bak1 antikoerper, bak1.L antikoerper

Hintergrund:

Synonyms: Apoptosis Regulator Bak, BAK 1, BAK, BAK like, Bak NT, BAK1, Bcl 2 homologous antagonist/killer, Bcl 2 like 7 protein, Bcl2 homologous antagonist killer, Bcl2 like 7 Protein, BCL2-antagonist/killer 1, BCL2L7, CDN 1, CDN1, Cell death inhibitor 1, MGC117255, MGC3887, NBak, Pro apoptotic protein BAK, BAX_MOUSE.

Background: In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2.

Gen-ID: 12018

UniProt: O08734

Pathways: Apoptose, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response