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TP53BP2 Antikörper (AA 1001-1128)

TP53BP2 Reaktivität: Human, Maus WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN674394
  • Target Alle TP53BP2 Antikörper anzeigen
    TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))
    Bindungsspezifität
    • 10
    • 9
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1001-1128
    Reaktivität
    • 54
    • 22
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 52
    • 2
    Kaninchen
    Klonalität
    • 44
    • 10
    Polyklonal
    Konjugat
    • 23
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TP53BP2 Antikörper ist unkonjugiert
    Applikation
    • 46
    • 22
    • 8
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus
    Homologie
    Rat,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ASPP2
    Isotyp
    IgG
    Top Product
    Discover our top product TP53BP2 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Xie, Yang, Chi, Yang, Wang, Xu: "Prognostic values of apoptosis-stimulating P53-binding protein 1 and 2 and their relationships with clinical characteristics of esophageal squamous cell carcinoma patients: a retrospective study." in: Chinese journal of cancer, Vol. 36, Issue 1, pp. 15, (2017) (PubMed).

  • Target
    TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))
    Andere Bezeichnung
    ASPP2/p53BP2 (TP53BP2 Produkte)
    Synonyme
    53BP2 antikoerper, ASPP2 antikoerper, BBP antikoerper, P53BP2 antikoerper, PPP1R13A antikoerper, TP53BP2 antikoerper, AI746547 antikoerper, Tp53bp2 antikoerper, X98550 antikoerper, Trp53bp2 antikoerper, wu:fa09h08 antikoerper, wu:fb04e08 antikoerper, zgc:85720 antikoerper, tumor protein p53 binding protein 2 antikoerper, tumor protein p53 binding protein 2 L homeolog antikoerper, tumor protein p53 binding protein, 2b antikoerper, transformation related protein 53 binding protein 2 antikoerper, tumor protein p53 binding protein, 2 antikoerper, tumor protein p53 binding protein, 2a antikoerper, TP53BP2 antikoerper, tp53bp2.L antikoerper, tp53bp2 antikoerper, tp53bp2b antikoerper, Trp53bp2 antikoerper, Tp53bp2 antikoerper, tp53bp2a antikoerper
    Hintergrund

    Synonyms: BBP, 53BP2, ASPP2, P53BP2, PPP1R13A, Apoptosis-stimulating of p53 protein 2, Bcl2-binding protein, Renal carcinoma antigen NY-REN-51, Tumor suppressor p53-binding protein 2, p53-binding protein 2, TP53BP2

    Background: Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.

    Gen-ID
    7159
    UniProt
    Q13625
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