TNFSF10 Antikörper (Tumor Necrosis Factor (Ligand) Superfamily, Member 10) (AA 215-265)

Details for Product anti-TNFSF10 Antibody No. ABIN673494, Anbieter: Anmelden zum Anzeigen
Antigen
  • TRAIL
  • tl2
  • apo2l
  • cd253
  • trail
  • apo-2l
  • trail1
  • xtrail1
  • APO2L
  • Apo-2L
  • CD253
  • TL2
  • A330042I21Rik
  • AI448571
  • APO-2L
  • Ly81
  • Trail
  • tumor necrosis factor (ligand) superfamily, member 10
  • TNF-related apoptosis inducing ligand-like
  • TNFSF10
  • TRAIL-LIKE
  • tnfsf10
  • Tnfsf10
Epitop
AA 215-265
41
26
14
7
6
6
5
4
4
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
321
73
33
3
3
2
1
1
1
Wirt
Kaninchen
190
153
24
2
1
Klonalität
Polyklonal
Konjugat
Dieser TNFSF10 Antikörper ist unkonjugiert
38
21
14
10
5
5
4
4
3
3
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
238
117
114
52
49
28
17
14
13
12
10
8
4
2
2
2
2
2
1
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen KLH conjugated synthetic peptide derived from human TRAIL
Isotyp IgG
Reinigung Purified by Protein A.
Andere Bezeichnung Trail (TNFSF10 Antibody Abstract)
Hintergrund

Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.

Subcellular location: Extracellular

Synonyms: TL2, APO2L, CD253, TRAIL, Apo-2L, Tumor necrosis factor ligand superfamily member 10, Apo-2 ligand, TNF-related apoptosis-inducing ligand, Protein TRAIL, TNFSF10

Gen-ID 8743
UniProt P50591
Forschungsgebiet Cancer, Apoptosis/Necrosis
Pathways Apoptose, Positive Regulation of Endopeptidase Activity
Applikationshinweise WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) (AA 215-265) antibody (ABIN673494) Formalin-fixed and paraffin embedded rat lung labeled with Anti-TRAIL Polyclonal Anti...
Immunohistochemistry (IHC) image for anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) (AA 215-265) antibody (ABIN673494) Formalin-fixed and paraffin embedded mouse spleen tissue labeled with Anti-TRAIL Poly...
Western Blotting (WB) image for anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) (AA 215-265) antibody (ABIN673494) Lane 1: Mouse lung lysates; Lane 2: U251 cell lysates probed with Anti–TRAIL Polyclon...
Produkt verwendet in: Seki, Cueno, Kamio, Saito, Kamimoto, Kurita-Ochiai, Ochiai et al.: "Varying butyric acid amounts induce different stress- and cell death-related signals in nerve growth factor-treated PC12 cells: implications in neuropathic pain absence during periodontal disease ..." in: Apoptosis : an international journal on programmed cell death, Vol. 21, Issue 6, pp. 699-707, 2016 (PubMed).

Fang, Zhang, Qi, Fan, Luo, Liu, Tan: "Evodiamine induces G2/M arrest and apoptosis via mitochondrial and endoplasmic reticulum pathways in H446 and H1688 human small-cell lung cancer cells." in: PLoS ONE, Vol. 9, Issue 12, pp. e115204, 2014 (PubMed).

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