Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

SPAG5 Antikörper (AA 1101-1193)

SPAG5 Reaktivität: Ratte ELISA, IF (cc), IF (p), IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN672261
  • Target Alle SPAG5 Antikörper anzeigen
    SPAG5 (Sperm Associated Antigen 5 (SPAG5))
    Bindungsspezifität
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1101-1193
    Reaktivität
    • 17
    • 1
    • 1
    • 1
    • 1
    Ratte
    Wirt
    • 16
    • 1
    Kaninchen
    Klonalität
    • 16
    • 1
    Polyklonal
    Konjugat
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SPAG5 Antikörper ist unkonjugiert
    Applikation
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Ratte
    Homologie
    Human,Mouse,Dog,Cow,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SPAG5/MAP126
    Isotyp
    IgG
    Top Product
    Discover our top product SPAG5 Primärantikörper
  • Applikationshinweise
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    SPAG5 (Sperm Associated Antigen 5 (SPAG5))
    Andere Bezeichnung
    SPAG5 (SPAG5 Produkte)
    Synonyme
    SPAG5 antikoerper, DEEPEST antikoerper, MAP126 antikoerper, hMAP126 antikoerper, AI874642 antikoerper, D11Bhm180e antikoerper, Deepest antikoerper, Mastrin antikoerper, S17 antikoerper, sperm associated antigen 5 antikoerper, sperm-associated antigen 5 antikoerper, SPAG5 antikoerper, LOC739263 antikoerper, Spag5 antikoerper
    Hintergrund

    Synonyms: MAP126, DEEPEST, hMAP126, Sperm-associated antigen 5, Astrin, Mitotic spindle-associated protein p126, SPAG5

    Background: Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase. Required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. In complex with SKAP, promotes stable microtubule-kinetochore attachments. May contribute to the regulation of separase activity. May regulate AURKA localization to mitotic spindle, but not to centrosomes and CCNB1 localization to both mitotic spindle and centrosomes. In non-mitotic cells, upon stress induction, inhibits mammalian target of rapamycin complex 1 (mTORC1) association and recruits the mTORC1 component RPTOR to stress granules (SGs), thereby preventing mTORC1 hyperactivation-induced apoptosis. May enhance GSK3B-mediated phosphorylation of other substrates, such as MAPT/TAU.

    Gen-ID
    10615
    UniProt
    Q96R06
    Pathways
    M Phase
Sie sind hier:
Kundenservice