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LDLR Antikörper (AA 781-860)

LDLR Reaktivität: Human, Maus, Ratte, Hamster, Pflanzen WB, ELISA, FACS, IF (p), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN672111
  • Target Alle LDLR Antikörper anzeigen
    LDLR (Low Density Lipoprotein Receptor (LDLR))
    Bindungsspezifität
    • 15
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 781-860
    Reaktivität
    • 75
    • 40
    • 26
    • 16
    • 15
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte, Hamster, Pflanzen
    Wirt
    • 63
    • 11
    • 5
    Kaninchen
    Klonalität
    • 62
    • 17
    Polyklonal
    Konjugat
    • 44
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LDLR Antikörper ist unkonjugiert
    Applikation
    • 58
    • 31
    • 26
    • 19
    • 12
    • 8
    • 7
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Hamster, Human, Maus, Pflanzen, Ratte
    Kreuzreaktivität (Details)
    Hamster
    Homologie
    Dog,Cow,Pig,Horse,Rabbit,Guinea Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human LDL-R
    Isotyp
    IgG
    Top Product
    Discover our top product LDLR Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Saxena, Kaur, Chandra: "Differential Response of B Cells to an Immunogen, a Mitogen and a Chemical Carcinogen in a Mouse Model System" in: Asian Pacific journal of cancer prevention : APJCP, Vol. 19, Issue 1, pp. 81-90, (2018) (PubMed).

    Kou, Han, Wang, Huang, He, Han, Zhou, Ye, Li: "Synergetic cholesterol-lowering effects of main alkaloids from Rhizoma Coptidis in HepG2 cells and hypercholesterolemia hamsters." in: Life sciences, Vol. 151, pp. 50-60, (2016) (PubMed).

    Jia, Song, Yang, Ma, Li, Lu, Cao, Zhang, Zhu, Wang, Leng, Cao, Du, Xu: "Effects of Tanshinone IIA on the modulation of miR‑33a and the SREBP‑2/Pcsk9 signaling pathway in hyperlipidemic rats." in: Molecular medicine reports, Vol. 13, Issue 6, pp. 4627-35, (2016) (PubMed).

    Gow, Muirhead, Hay, Argyle: "Low-Density Lipoprotein Uptake Demonstrates a Hepatocyte Phenotype in the Dog, but Is Nonspecific." in: Stem cells and development, Vol. 25, Issue 1, pp. 90-100, (2015) (PubMed).

    Wu, He, Wang, Xue, Ning, Zou, Ye, Li, Wang, Pang: "The antihypercholesterolemic effect of jatrorrhizine isolated from Rhizoma Coptidis." in: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 21, Issue 11, pp. 1373-81, (2014) (PubMed).

  • Target
    LDLR (Low Density Lipoprotein Receptor (LDLR))
    Andere Bezeichnung
    LDL receptor (LDLR Produkte)
    Synonyme
    FH antikoerper, FHC antikoerper, LDLCQ2 antikoerper, Hlb301 antikoerper, LDLRA antikoerper, LDLA antikoerper, LDL receptor-2 antikoerper, fhc antikoerper, ldlcq2 antikoerper, ldlr antikoerper, ldlr2-a antikoerper, LDL receptor 1 antikoerper, ldlr-a antikoerper, ldlr-b antikoerper, low density lipoprotein receptor antikoerper, low density lipoprotein receptor a antikoerper, low density lipoprotein receptor S homeolog antikoerper, low density lipoprotein receptor L homeolog antikoerper, LDLR antikoerper, Ldlr antikoerper, ldlra antikoerper, ldlr.S antikoerper, ldlr.L antikoerper
    Hintergrund

    Synonyms: FH, FHC, LDLCQ2, Low-density lipoprotein receptor, LDL receptor, LDLR

    Background: Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells.

    Gen-ID
    3949
    UniProt
    P01130
    Pathways
    Hepatitis C, Lipid Metabolism
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