» Antikörper » anti-ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (ABCG2) Antikörper (Cy5)

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	+49 (0)241 95 163 153
	+49 (0)241 95 163 155

ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (ABCG2) Antikörper (Cy5)

Antigen	ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (ABCG2)
Synonyme	MRX, MXR, ABCP, BCRP, BMDP, MXR1, ABC15, BCRP1, CD338, CDw338, EST157481, MGC102821, Bcrp1, AI428558, ABCG2, MGC127688, bcrp
Klonalität	Polyklonal
Wirt	Alternativen Kaninchen Maus (43), Kaninchen (38), Ratte (5)
Reaktivität	Alternativen Human, Ratte (Rattus), Maus Human (77), Maus (29), Ratte (Rattus) (17), Rind (Kuh) (4), Hund (3), Affe (3), Schwein (2), Huhn (1), Escherichia Coli (E. Coli) (1)
Konjugat	Alternativen Cy5 Biotin (6), PE (6), FITC (3), APC (1), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Applikation	Alternativen Durchflusszytometrie (FACS), Immunfluoreszenz (IF) Durchflusszytometrie (FACS) (52), Western Blot (WB) (44), Immunfluoreszenz (IF) (31), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (21), Immunhistochemie (Paraffinschnitte) (IHC (p)) (12), ELISA (8), Enzyme Immunoassay (EIA) (6), Immunhistochemie (IHC) (4), Immunzytochemie (ICC) (3), ELISA (Detektionsantikörper) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunpräzipitation (IP) (2), Dot Blot (Dot) (1), Funktionale Studien (Func) (1), Immunoelectron Microscopy (IEM) (1)

Produktnummer	ABIN671605
Menge	100 µg (1mg/1ml)
Preis	290,60 € Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit	Lieferung in 10 bis 15 Werktagen

Produktbeschreibung
Anwendungen Alternativen zurück nach oben

Weitere Bezeichnung	ABCG2
Immunogen	Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human ABCG2
Format	Lyophilized
Wiederherstellung	Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)
Isotyp	IgG
Beschreibung	Synonym: BCRP, BXP-21, ABC15, ABCG 2, ABCG2, ABCP, ATP-binding cassette sub-family G member 2, BCRP1, BMDP, Breast cancer resistance protein, CDw338, CDw338, CD338, antigen, EST157481, MGC102821, Mitoxantrone resistance associated protein, MRX, MXR, MXR1, Placenta-specific ATP-binding cassette transporter.
Spezifität	Excitation / Emission Wavelengths: 650nm/670nm
Molekulargewicht	72kDa
Kommentare	An ABC transporter. Allows efflux of Hoechst dye a property that has been used to separate bone marrow side population cells which express BCRP/ABCG2. Appears to play a major role in the multidrug resistance phenotype of a specific MCF-7 breast cancer cell line. When overexpressed the transfected cells become resistant to mitoxantrone daunorubicin and doxorubicin display diminished intracellular accumulation of daunorubicin and manifest an ATP-dependent increase in the efflux of rhodamine 123.. Breast Cancer Resistance Protein (BCRP) is a 70 kDa ATP-Binding Cassette membrane transport protein involved in multidrug resistance. BCRP may be over-expressed in cancer cell lines selected with doxorubicin / verapamil topotecan or mitoxantrone.

Anwendungen
Alternativen zurück nach oben

Applikationshinweise	Flow-Cyt (1:50-200), IF (1:50-200)
Konzentration	1mg/1ml
Reinigung	Antibodies are purified by protein A and peptide affinity chromatography.
Buffer	0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
Lagerung	Ship at room temperature. Store at -20°C
Forschungsgebiet	Transporter
Beschränkungen	Nur für Forschungszwecke einsetzbar

Alternativen
Anwendungen zurück nach oben

Alternativen zu Antigen "ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (ABCG2)", Typ "Antikörper" finden

Wirte	Maus (43), Kaninchen (38), Ratte (5)
Reaktivitäten	Human (77), Maus (29), Ratte (Rattus) (17), Rind (Kuh) (4), Hund (3), Affe (3), Schwein (2), Huhn (1), Escherichia Coli (E. Coli) (1)
Applikationen	Durchflusszytometrie (FACS) (52), Western Blot (WB) (44), Immunfluoreszenz (IF) (31), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (21), Immunhistochemie (Paraffinschnitte) (IHC (p)) (12), ELISA (8), Enzyme Immunoassay (EIA) (6), Immunhistochemie (IHC) (4), Immunzytochemie (ICC) (3), ELISA (Detektionsantikörper) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunpräzipitation (IP) (2), Dot Blot (Dot) (1), Funktionale Studien (Func) (1), Immunoelectron Microscopy (IEM) (1)
Konjugate	Biotin (6), PE (6), FITC (3), APC (1), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitope	C-Term (2), Center (2)