STAM2 Antikörper (AA 143-172)

Produktnummer ABIN657963

Produktdetails anti-STAM2 Antikörper

Target: STAM2 (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))

Bindungsspezifität: AA 143-172

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STAM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This STAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-172 amino acids from the Central region of human STAM2.

Klon: RB34085

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: STAM2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu STAM2

Target: STAM2 (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))

Andere Bezeichnung: STAM2 (STAM2 Produkte)

Synonyme: Hbp antikoerper, STAM2A antikoerper, STAM2B antikoerper, 1200004O12Rik antikoerper, 5730456G07Rik antikoerper, BB145015 antikoerper, stam2 antikoerper, MGC52950 antikoerper, zgc:103628 antikoerper, signal transducing adaptor molecule 2 antikoerper, signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 antikoerper, signal transducing adaptor molecule 2 S homeolog antikoerper, STAM2 antikoerper, Stam2 antikoerper, stam2.S antikoerper, stam2 antikoerper

Hintergrund: The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation.

Molekulargewicht: 58164

Gen-ID: 10254

NCBI Accession: NP_005834

UniProt: O75886

Pathways: EGFR Signaling Pathway, EGFR Downregulation